Chemical constituents of the endophytic fungal strain Phomopsis sp NXZ-05 of Camptotheca acuminata

被引:31
|
作者
Tan, Qifang
Yan, Xuefen
Lin, Xiang
Huang, Yaojian
Zheng, Zhonghui
Song, Siyang
Lu, Chunhua
Shen, Yuemao
机构
[1] Xiamen Univ, Key Lab Cell Biol & Tumor Cell Engn, Minist Educ, Fujian 361005, Peoples R China
[2] Xiamen Univ, Xiamen Engn Res Ctr Marine Microbial Drug Discove, Fujian 361005, Peoples R China
[3] Xiamen Univ, Sch Life Sci, Fujian Lab Pharmaceut Engn, Fujian 361005, Peoples R China
关键词
D O I
10.1002/hlca.200790190
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
From the endophytic fungal strain Phomopsis sp. NXZ-05 of Camptotheca acuminata DECNE. (Nyssaceae), six new compounds were isolated, including the ten-membered macrolides 1-4 and their (known) parent compound multiplolide A (7), as well as a new unsaturated fatty acid, (4E)-6,7,9-trihydroxydec-4-enoic acid (5) and its methyl ester 6. Their structures were elucidated by spectroscopic and mass-spectrometric analyses, including 1D- and 2D-NMR experiments and HR-ESI-MS, and their biological activities were elucidated.
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页码:1811 / 1817
页数:7
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