Living with epilepsy -: Long-term prognosis and psychosocial outcomes

被引:104
|
作者
Shackleton, DP
Trenité, DGAKN
de Craen, AJM
Vandenbroucke, JP
Westendorp, RGJ
机构
[1] Stichting Epilepsie Instellingen Nederland, Heemstede, Netherlands
[2] Leiden Univ, Fac Med, Dept Clin Epidemiol, NL-2300 RA Leiden, Netherlands
关键词
D O I
10.1212/01.WNL.0000073543.63457.0A
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: To analyze the impact of seizures on everyday life and the long-term effects of epilepsy on health status and psychosocial outcomes. Methods: Follow-up study was conducted of a cohort of consecutive patients newly diagnosed with epilepsy between 1953 and 1967. In 1995 (mean follow-up 34 years), a random sample of 333 patients received a questionnaire asking clinical and demographic information and validated measures for psychosocial outcomes. Comparisons were made with the general Dutch population. Results: The response rate was 73% (116 men and 127 women); mean age was 49.9 years (SD 11.2 years). Mean age at epilepsy onset was 15 years (SD 11 years); mean duration was 24.4 years (SD 13.1 years). In total, 134 (55%; 72 men and 62 women) patients were seizure-free for the previous 5 years, and 81 patients still had seizures in the last year. One hundred twenty-seven patients were taking antiepileptic drugs, of which 51 were on monotherapy. Epilepsy patients have a positive health evaluation, comparable with the general Dutch population. Fewer epilepsy patients married or had children than the general Dutch population; more patients live at home with their parents or in foster homes or institutions (p < 0.001). Having epilepsy at school age has a significant negative effect on learning achievement (p < 0.01). Employment status is affected less, though more epilepsy patients are unfit to work than individuals from the general population (p < 0.05). Conclusions: Epilepsy has a marked negative impact on education and achievement in later life. Despite worse psychosocial outcomes than the Dutch population, patients with epilepsy cope well with their epilepsy, regardless of their handicaps.
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页码:64 / 70
页数:7
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