Renewing the Fight Against TB with an Old Vaccine

被引：6
|
作者：
Scriba, Thomas J. [1 ,2 ]
Mizrahi, Valerie [3 ,4 ,5 ]
机构：
[1] Univ Cape Town, South African TB Vaccine Initiat, Cape Town, South Africa
[2] Univ Cape Town, Inst Infect Dis & Mol Med, Div Immunol, Dept Pathol, Cape Town, South Africa
[3] Univ Cape Town, SAMRC NHLS UCT Mol Mycobacteriol Res Unit, Cape Town, South Africa
[4] Univ Cape Town, Inst Infect Dis & Mol Med, Div Med Microbiol, Dept Pathol, Cape Town, South Africa
[5] Univ Cape Town, Wellcome Ctr Infect Dis Res Africa, Cape Town, South Africa
来源：
CELL | 2020年 / 180卷 / 05期
关键词：
TUBERCULOSIS; BCG; PREVENTION; MACAQUES;
D O I：
10.1016/j.cell.2020.02.024
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Prevention of pulmonary tuberculosis by vaccination has proven an elusive goal. In a recent study, Darrah et al. show that prevention of infection and disease can be achieved in non-human primates by intravenous administration of the century-old vaccine BCG. This finding heralds a step-change in the approach to TB vaccine development.
引用
收藏
页码：829 / 831
页数：3
相关论文
共 50 条
  • [1] The latest effort in the fight against TB
    不详
    [J]. R&D MAGAZINE, 2003, 45 (12): : 14 - 14
  • [2] PRESENT TRENDS IN FIGHT AGAINST TB
    HITZE, KL
    [J]. REVISTA MEDICA DE CHILE, 1973, 101 (10) : 808 - 812
  • [3] A vaccine can't wait - Old rivalries are hampering the fight against AIDS
    不详
    [J]. NEW SCIENTIST, 2002, 173 (2327) : 3 - 3
  • [4] Tuberculosis vaccine BCG: the magical effect of the old vaccine in the fight against the COVID-19 pandemic
    Aspatwar, Ashok
    Gong, Wenping
    Wang, Shuyong
    Wu, Xueqiong
    Parkkila, Seppo
    [J]. INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2022, 41 (02) : 283 - 296
  • [5] World TB Day 2017: Strengthening the fight against TB
    Solovic, Ivan
    Centis, Rosella
    D'Ambrosio, Lia
    Visca, Dina
    Migliori, Giovanni Battista
    [J]. PRESSE MEDICALE, 2017, 46 (02): : E1 - E4
  • [6] FIGHT AGAINST OLD AGE
    CHEBOTAREV, D
    [J]. GERONTOLOGIST, 1971, 11 (04): : 359 - +
  • [7] UNSEEN FIGHT AGAINST CANCER - DUNN,TB
    MEDAWAR, PB
    [J]. NEW YORK REVIEW OF BOOKS, 1977, 24 (10) : 10 - 14
  • [8] Russian oblast is model in fight against TB
    Zolotova, Elena
    [J]. BULLETIN OF THE WORLD HEALTH ORGANIZATION, 2007, 85 (05) : 329 - 331
  • [9] WHO steps up fight against TB
    Tamber, PS
    [J]. BRITISH MEDICAL JOURNAL, 1996, 312 (7034): : 796 - 796
  • [10] Renewing the politics of cooperation and development in the fight against poverty in developing countries
    Levy, M
    [J]. ESPRIT, 2000, (06) : 79 - 100
12345