机构:
First Peoples Hosp Xuzhou, Dept Neurol, Div 2, Xuzhou 221000, Jiangsu, Peoples R ChinaFirst Peoples Hosp Xuzhou, Dept Neurol, Div 2, Xuzhou 221000, Jiangsu, Peoples R China
Huang, Hongli
[1
]
Zhou, Hao
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机构:
First Peoples Hosp Xuzhou, Dept Neurol, Div 2, Xuzhou 221000, Jiangsu, Peoples R ChinaFirst Peoples Hosp Xuzhou, Dept Neurol, Div 2, Xuzhou 221000, Jiangsu, Peoples R China
Zhou, Hao
[1
]
Wang, Nuan
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机构:
First Peoples Hosp Xuzhou, Dept Neurol, Div 2, Xuzhou 221000, Jiangsu, Peoples R ChinaFirst Peoples Hosp Xuzhou, Dept Neurol, Div 2, Xuzhou 221000, Jiangsu, Peoples R China
Wang, Nuan
[1
]
机构:
[1] First Peoples Hosp Xuzhou, Dept Neurol, Div 2, Xuzhou 221000, Jiangsu, Peoples R China
HFOs High frequency oscillations;
Epilepsy;
Seizure localization;
HIGH-FREQUENCY OSCILLATIONS;
NEOCORTICAL EPILEPSY;
ANTIEPILEPTIC DRUGS;
SURGICAL-TREATMENT;
SEIZURES;
RESECTION;
MECHANISMS;
THERAPY;
NETWORK;
EEG;
D O I:
10.1007/s12013-015-0603-y
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
One of the most common neurological disorders is epilepsy, which, approximately affecting more than 40 million people worldwide. The situation worsens in the affected patient when the epilepsy becomes intractable, that simply means failure of anti-epileptic drugs (AED) to achieve seizure freedom. It is also associated with an increased prevalence of mental health disorders including anxiety, depression, and suicidal thoughts. The present review is focused on the recent advances being utilized world over for the effective management of epilepsy patients. The review article discusses the efficacy and importance of recent AED drugs in use for management of epilepsy on one hand and on other hand highlights the use of modern advancements like High frequency oscillations, Network analysis, Seizure localization, Epilepsy surgery in curing intractable epilepsy.
机构:
Oregon Hlth & Sci Univ, Dept Neurol, L226,3181 SW Sam Jackson Pk Rd, Portland, OR 97239 USA
VA Portland Healthcare Syst, Epilepsy Ctr Excellence, Portland, OR USAOregon Hlth & Sci Univ, Dept Neurol, L226,3181 SW Sam Jackson Pk Rd, Portland, OR 97239 USA
Ernst, Lia D.
Boudreau, Eilis A.
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机构:
Oregon Hlth & Sci Univ, Dept Neurol, L226,3181 SW Sam Jackson Pk Rd, Portland, OR 97239 USA
VA Portland Healthcare Syst, Epilepsy Ctr Excellence, Portland, OR USA
Oregon Hlth & Sci Univ, Dept Med Informat & Clin Epidemiol, Portland, OR 97201 USAOregon Hlth & Sci Univ, Dept Neurol, L226,3181 SW Sam Jackson Pk Rd, Portland, OR 97239 USA
机构:
St Georges NHS Trust, Atkinson Morley Epilepsy Grp, London SW17 0QT, EnglandUniv London, Div Clin Sci, London SW17 0RE, England
Lozsadi, Dora A.
Von Oertzen, Joachim
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机构:
St Georges NHS Trust, Atkinson Morley Epilepsy Grp, London SW17 0QT, EnglandUniv London, Div Clin Sci, London SW17 0RE, England
Von Oertzen, Joachim
Cock, Hannah R.
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机构:
Univ London, Div Clin Sci, London SW17 0RE, England
St Georges NHS Trust, Atkinson Morley Epilepsy Grp, London SW17 0QT, EnglandUniv London, Div Clin Sci, London SW17 0RE, England