Passive or active fluctuations in membranes containing proteins

被引:52
|
作者
Girard, P
Prost, J
Bassereau, P
机构
[1] Inst Curie, UMR 168, CNRS, F-75231 Paris 05, France
[2] Ecole Super Phys & Chim Ind Ville Paris, F-75231 Paris 05, France
关键词
D O I
10.1103/PhysLettRev.94.088102
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We have experimentally investigated the effect of a transmembrane protein, the Ca2+-ATPase, on shape fluctuations of giant vesicles. By using the micropipette method, we have measured a substantial renormalization of the bending modulus due to the presence of proteins in the membrane. Moreover, we have produced the first quantitative measurement of the active force dipole associated with the amplification of the fluctuations when the proteins are activated by adenosine 5'-triphosphate (ATP).
引用
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页数:4
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