Discovery and structure-activity relationship (SAR) of novel pyridylureas as potent antibacterial agents

被引：0
|
作者：
Bist, Shanta [1 ]
Basarab, Greg [1 ]
Manchester, John [1 ]
Sherer, Brian [2 ]
机构：
[1] AstraZeneca R&D Boston, Waltham, MA 02451 USA
[2] EMD Serono Res & Dev Inst, Billerica, MA 01821 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 247卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
107-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [1] 4-PYRIDYLUREAS ARE SURPRISINGLY POTENT CYTOKININS - THE STRUCTURE-ACTIVITY RELATIONSHIP
    OKAMOTO, T
    SHUDO, K
    TAKAHASHI, S
    KAWACHI, E
    ISOGAI, Y
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1981, 29 (12) : 3748 - 3750
  • [2] Design, Synthesis, and Structure-Activity Relationship Studies of Novel Thioether Pleuromutilin Derivatives as Potent Antibacterial Agents
    Ling, Chenyu
    Fu, Liqiang
    Gao, Suo
    Chu, Wenjing
    Wang, Hui
    Huang, Yanqin
    Chen, Xiaoyan
    Yang, Yushe
    JOURNAL OF MEDICINAL CHEMISTRY, 2014, 57 (11) : 4772 - 4795
  • [3] Discovery of novel heteroarylmethylcarbamodithioates as potent anticancer agents: Synthesis, structure-activity relationship analysis and biological evaluation
    Li, Ying-Bo
    Yan, Xu
    Li, Ri-Dong
    Liu, Peng
    Sun, Shao-Qian
    Wang, Xin
    Cui, Jing-Rong
    Zhou, De-Min
    Ge, Ze-Mei
    Li, Run-Tao
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 112 : 217 - 230
  • [4] Design, Synthesis, and Structure-Activity Relationship Studies of Highly Potent Novel Benzoxazinyl-Oxazolidinone Antibacterial Agents
    Xin, Qisheng
    Fan, Houxing
    Guo, Bin
    He, Huili
    Gao, Suo
    Wang, Hui
    Huang, Yanqin
    Yang, Yushe
    JOURNAL OF MEDICINAL CHEMISTRY, 2011, 54 (21) : 7493 - 7502
  • [5] Discovery of a novel class of rosmarinic acid derivatives as antibacterial agents: Synthesis, structure-activity relationship and mechanism of action
    Wang, Yong
    Liang, Zhiguang
    Cao, Yihui
    Hung, Cheung-Hin
    Du, Ruolan
    Leung, Alan Siu-Lun
    So, Pui-Kin
    Chan, Pak-Ho
    Wong, Wing-Leung
    Leung, Yun-Chung
    Wong, Kwok-Yin
    BIOORGANIC CHEMISTRY, 2024, 146
  • [6] The structure-activity relationship (SAR) of and novel molecular mechanisms for ginsenosides as anticancer agents
    Wang, Wei
    Chen, Haiyan
    Zhao, Yuqing
    Wang, Hui
    Zhang, Ruiwen
    CANCER RESEARCH, 2006, 66 (08)
  • [7] Discovery of a New Class of Highly Potent Inhibitors of Acid Ceramidase: Synthesis and Structure-Activity Relationship (SAR)
    Pizzirani, Daniela
    Pagliuca, Chiara
    Realini, Natalia
    Branduardi, Davide
    Bottegoni, Giovanni
    Mor, Marco
    Bertozzi, Fabio
    Scarpelli, Rita
    Piomelli, Daniele
    Bandiera, Tiziano
    JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (09) : 3518 - 3530
  • [8] Dihydropyrimidinones as potent anticancer agents: Insight into the structure-activity relationship
    Prasad, Tanya
    Mahapatra, Aastha
    Sharma, Tripti
    Sahoo, Chita R.
    Padhy, Rabindra Nath
    ARCHIV DER PHARMAZIE, 2023, 356 (06)
  • [9] Structure-activity relationship (SAR) and antibacterial activity of pyrrolidine based hybrids: A review
    Bhat, Aeyaz Ahmad
    Tandon, Nitin
    Singh, Iqubal
    Tandon, Runjhun
    JOURNAL OF MOLECULAR STRUCTURE, 2023, 1283
  • [10] Design, Synthesis and Structure-Activity Relationship Study of Coumarin Benzimidazole Hybrid as Potent Antibacterial and Anticancer Agents
    Holiyachi, Megharaja
    Shastri, Samundeeswari L.
    Chougala, Bahubali M.
    Shastri, Lokesh A.
    Joshi, Shrinivas D.
    Dixit, Sheshagiri R.
    Nagarajaiah, Honnappa
    Sunagar, Vinay A.
    CHEMISTRYSELECT, 2016, 1 (15): : 4638 - 4644
12345