Childhood Acute Lymphoblastic Leukemia with Near-Tetraplody and t(12;21) (p13;q22) Trans location: A Case Report

被引：0
|
作者：
Karkucak, Mutlu [1 ]
Yakut, Tahsin [1 ]
Baytan, Birol [2 ]
Gulten, Tuna [1 ]
Gunes, A. Meral [2 ]
机构：
[1] Uludag Univ, Tip Fak, Tibbi Genet Anabilim Dali, TR-16059 Bursa, Turkey
[2] Uludag Univ, Fac Med, Dept Pediat Hematol, TR-16059 Bursa, Turkey
来源：
UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI | 2011年 / 21卷 / 03期
关键词：
Childhood acute lymphoblastic leukemia; Near-Tetraploidy; t(12; 21); MOLECULAR-GENETICS; HYPERDIPLOIDY; TEL-AML1; CHILDREN;
D O I：
10.4999/uhod.09122
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Fluroscent in situ hybridization analysis indicated presence of t(12;21)(p13;q22) translocation and near-tetraploidy in a case who 11-year-old boy and diagnosed with B precursor acute lymphoblastic leukemia (ALL). Although, some studies suggest good prognostic effect of translocation t(12;21) (p13;q22), there were very little data regarding the prognostic effect of Near-tetraploidy. Here we discussed the prognostic relevance of both t(12;21)(p13;q22) translocation and near tetraplody in Pre-B ALL.
引用
收藏
页码：192 / 195
页数：4
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