TRIMing Neural Connections with Ubiquitin

被引：6

作者：

Montell, Denise J. ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Mol Cellular & Dev Biol, Santa Barbara, CA 93106 USA

来源：

DEVELOPMENTAL CELL | 2019年 / 48卷 / 01期

关键词：

DCC;

D O I：

10.1016/j.devcel.2018.12.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During evolution, ubiquitin ligases increased in number with increasing nervous system complexity. Recent work shows that proper brain development, cognitive ability, and social behavior in mice require the ubiquitin ligase TRIM67. The work illuminates how general regulators like ubiquitin promote specific functions such as nervous system wiring during development.

引用

页码：5 / 6

页数：2

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