Structural and thermal characterization of cerium, thorium and uranyl complexes of sulfasalazine

Cerium(IV), Thorium(IV) and Uranyl(11) complexes with the ammonium salt of sulfasalazine drug (H(2)SSZ, HL-) have been studied. The structures of the complexes were elucidated using elemental analysis, IR and mass spectroscopy and thermal analysis. The complexes were isolated in 1:1 and 1:2 (M:L) ratios. The solid monocomplexes (1: 1) (M:H(2)SSZ) were isolated in the general formulae [UO2(L)(H2O)(2)]center dot 2H(2)O and [M(L)(X)(z)(H2O)(n)]center dot yH(2)O (M = Ce(IV) and Th(IV) (X = NO3, z = 2, n = 2, y = 0-3)). The biscomplexes (1:2) (M:H(2)SSZ) solid chelates found to have the general formulae [UO2(HL)(2)]center dot 2H(2)O and [M(L)(2)(H2O)(2)] (M=Ce(IV) and Th(IV)). The thermal decomposition of the complexes should be discussed in relation to structure, and the thermodynamic parameters of the decomposition stages were evaluated applying Coats-Redfern and Horwitz-Mitzger methods. (c) 2005 Elsevier B.V. All rights reserved.