Sustainable approach for development of antimicrobial textile material using nanoemulsion for wound care applications

Development of nanostructured textile material using sustainable finishing route and to evaluate its performance in the areas like wound management is challenging task. Stable and eco-friendly o/w nanoemulsion of tetrahydroxy curcumin derivative was developed by using high pressure homogenization method. The stable nanoemulsion for the selected drug was developed and evaluated for appearance, particle size distribution (100-300nm), zeta potential (-30.1 to -31.1mV) and drug content (80-83.3%). Nanoemulsion containing antimicrobial drug were impregnated on the textile material by exhaust methods using -cyclodextrin and polycarboxylic acid as a crosslinking agent. Treated textile material is evaluated for its antimicrobial activity against standard antimicrobial strip using both AATCC 147 and AATCC 100, treated samples shows positive results against both positive and negative bacteria. Current eco-friendly technique would be innovative step towards development of medical textile for wound care applications.