Carbapenem resistance among Escherichia coli and Klebsiella pneumoniae in a tertiary care hospital in south India

被引：43
|
作者：
Nagaraj, S. [2 ]
Chandran, S. P. [1 ,2 ]
Shamanna, P. [2 ]
Macaden, R. [1 ]
机构：
[1] St Johns Res Inst, Infect Dis Unit, Bangalore 560034, Karnataka, India
[2] St Johns Med Coll, Dept Microbiol, Bangalore 560034, Karnataka, India
来源：
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY | 2012年 / 30卷 / 01期
关键词：
Antibiotic resistance; carbapenemases; New Delhi metallo-beta-lactamase; BETA; THREAT;
D O I：
10.4103/0255-0857.93054
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Carbapenem resistance among clinical isolates of Enterobacteriaceae, especially Escherichia coli and Klebsiella pneumoniae, is largely conferred by metallo-beta-lactamase (MBL). Fifty-one non repetitive isolates of carbapenem-resistant (Meropenem and Imipenem) E. coli and K. pneumoniae were studied to determine the molecular mechanism for resistance. Presence of bla(NDM) and bla(VIM) was determined by polymerase chain reaction (PCR) and DNA sequencing. bla(NDM) was detected from majority of carbapenem-resistant K. pneumoniae (75%) and E. coli (66.6%). Timely detection and appropriate and aggressive infection control measures are required to control the spread of these bacteria in healthcare settings.
引用
收藏
页码：93 / 95
页数：3
相关论文
共 50 条
  • [1] CARBAPENEM RESISTANCE PROFILE AMONGST ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE IN A TERTIARY CARE HOSPITAL IN AHMEDNAGAR, MAHARASHTRA
    Gunjal, Shraddha Prasad
    Gunjal, Prasad Niranjan
    Vanaparthi, Nagaraju
    Sudheer, Kher
    INTERNATIONAL JOURNAL OF MEDICAL RESEARCH & HEALTH SCIENCES, 2014, 3 (02): : 424 - 427
  • [2] CARBAPENEM RESISTANCE IN ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE AMONG INDIAN AND INTERNATIONAL PATIENTS IN NORTH INDIA
    Jaggi, Namita
    Chatterjee, Nirupama
    Singh, Vyoma
    Giri, Santosh Kumar
    Dwivedi, Priyambada
    Panwar, Rajesh
    Sharma, Ajendra Pratap
    ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA, 2019, 66 (03) : 367 - 376
  • [3] Extended spectrum β-lactamases of Escherichia coli and Klebsiella pneumoniae in a South Indian tertiary care hospital
    Navaneeth, BV
    Sridaran, D
    Indumathi, VA
    Babu, PRS
    Devi, DRG
    Belwadi, MRS
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2002, 20 (04) : 309 - 310
  • [4] Molecular Detection of Carbapenem Resistance in Clinical Isolates of Klebsiella pneumoniae in Tertiary Care Hospital
    Patil, Praful S.
    Shah, Harshada
    Singh, Brij Nandan
    Chandi, Dhruba Hari
    Deb, Mrinangka
    Jha, Roshan
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2023, 17 (02): : 1109 - 1117
  • [5] Detection of TEM & SHV genes in Escherichia coli & Klebsiella pneumoniae isolates in a tertiary care hospital from India
    Sharma, Jyoti
    Sharma, Meera
    Ray, Pallab
    INDIAN JOURNAL OF MEDICAL RESEARCH, 2010, 132 (03) : 332 - 336
  • [6] Prevalence of extended-spectrum β-lactamases among Escherichia coli and Klebsiella pneumoniae isolates in a tertiary care hospital
    Agrawal, Parul
    Ghosh, A. N.
    Kumar, Satish
    Basu, B.
    Kapila, K.
    INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2008, 51 (01) : 139 - 142
  • [7] Genetic determination and characterization of extended spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae in a tertiary care hospital, India
    Padmini, Nagarajan
    Ajilda, Antony Alex Kennedy
    Sivakumar, Natesan
    Sureka, Indrajith
    Kumar, Ramasamy Senthil
    Selvakumar, Gopal
    INDIAN JOURNAL OF BIOTECHNOLOGY, 2019, 18 (02): : 145 - 150
  • [8] Investigation of blaKPC Gene by PCR in Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae Clinical Isolates in a Tertiary Care Hospital in Turkey
    Ozyazici, Gonca
    Ozkaya, Esra
    Kaya, Havva
    Kocaturk Sel, Sabriye
    Altinbasak, Hasan
    Basari, Fesem
    Suntur, Bedia Mutay
    Buruk, Celal Kurtulus
    MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, 2019, 8
  • [9] Current Status Of Carbapenem Resistance In Tertiary Care Referral Hospital In South India
    Soundarapandian, S.
    Manju, R.
    Thangavel, N. S.
    Manikandan, M.
    INTERNATIONAL JOURNAL OF LIFE SCIENCE AND PHARMA RESEARCH, 2022, 12 : 53 - 59
  • [10] ESBL-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care hospital in Saudi Arabia
    Somily, Ali M.
    Habib, Hanan A.
    Absar, Muhammad M.
    Arshad, Muhammad Z.
    Manneh, Kutubu
    Al Subaie, Sarah S.
    Al Hedaithy, Mogbil A.
    Sayyed, Samina B.
    Shakoor, Zahid
    Murray, Thomas S.
    JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, 2014, 8 (09): : 1129 - 1136
12345