Synthesis of enantiomerically pure N-(S)-alpha-methylbenzyl-beta-aminoalcohols by regio- and stereoselective ring opening of epoxides

被引：0
|
作者：
deParrodi, CA
Juaristi, E
QuinteroCortes, L
机构：
[1] INST POLITECN NACL,CTR INVEST & ESTUDIOS AVANZADOS,DEPT QUIM,MEXICO CITY 07000,DF,MEXICO
[2] UNIV LAS AMER PUEBLA,DEPT QUIM & BIOL,CHOLULA 72820,PUEBLA,MEXICO
[3] UNIV AUTONOMA PUEBLA,FAC CIENCIAS QUIM,CTR INVEST,PUEBLA 72570,MEXICO
来源：
ANALES DE QUIMICA | 1996年 / 92卷 / 06期
关键词：
beta-aminoalcohols; enantiopure; chiral ligands; regioselective; stereoselective;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A high yield, stereoselective ring opening of symmetrically substituted epoxides with (S)-alpha-methylbenzylamine to produce enantiomerically pure N-(S)-alpha-methylbenzyl-beta-aminoalcohols is described. In addition, the regioselective ring opening of (R)-styrene oxide with (S)-alpha-methylbenzylamine and enantiomerically pure secondary amines, (S)-N-benzyl-, (S)-N-isopropyl-, (S)-N-[(2-biphenyl)methyl]-alpha-methylbenzylamine is described.
引用
收藏
页码：400 / 404
页数：5
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