Sugar defeats the Hippo: Glycogen regulation of the Hippo pathway in liver

被引：2
|
作者：
Nguyen-Lefebvre, Anh Thu [1 ,2 ]
Bhat, Mamatha [1 ]
Wrana, Jeffrey L. [2 ,3 ]
机构：
[1] Toronto Gen Hosp, Dept Med, Multiorgan Transplant Program, Toronto, ON, Canada
[2] Lunenfeld Tanenbaum Res Inst, Toronto, ON, Canada
[3] Univ Toronto, Dept Mol Genet, Toronto, ON, Canada
来源：
MOLECULAR CELL | 2021年 / 81卷 / 23期
关键词：
SIZE;
D O I：
10.1016/j.molcel.2021.11.008
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Liver glycogen is famous for glucose storage, but new work by Liu et al. (2021) now reveals that it's been hiding a few secrets and can directly promote liver enlargement and tumorigenesis by sequestering the tumor suppressive Hippo signaling pathway.
引用
收藏
页码：4768 / 4770
页数：3
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