Inhibition of the PI3K p110α impairs cell survival, chemoresistance and invasion in human medulloblastoma cells

被引:0
|
作者
Guerreiro, Ana [1 ]
Fattet, Sarah [2 ]
Shalaby, Tarek [3 ]
Grotzer, Michael A. [3 ]
Delattre, Olivier [2 ]
Arcaro, Alexandre [1 ]
机构
[1] Univ Childrens Hosp Zurich, Div Clin Chem & Biochem, Zurich, Switzerland
[2] Inst Curie, Lab Pathol Mol Canc, Paris, France
[3] Univ Childrens Hosp Zurich, Dept Oncol, Program Neurooncol, Zurich, Switzerland
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:3551S / 3552S
页数:2
相关论文
共 50 条
  • [1] Targeting PI3KP110 impairs survival, chemoresistance, and invasion in human medulloblastoma cells
    Guerreiro, Ana S.
    Fattet, Sarah
    Shalaby, Tarek
    Grotzer, Michael A.
    Delattre, Olivier
    Arcaro, Alexandre
    [J]. NEURO-ONCOLOGY, 2008, 10 (03) : 514 - 514
  • [2] Targeting the PI3K p110α Isoform Inhibits Medulloblastoma Proliferation, Chemoresistance, and Migration
    Guerreiro, Ana S.
    Fattet, Sarah
    Fischer, Barbara
    Shalaby, Tarek
    Jackson, Shaun P.
    Schoenwaelder, Simone M.
    Grotzer, Michael A.
    Delattre, Olivier
    Arcaro, Alexandre
    [J]. CLINICAL CANCER RESEARCH, 2008, 14 (21) : 6761 - 6769
  • [3] A sensitized RNA interference screen identifies a novel role for the PI3K p110\#947; isoform in medulloblastoma cell survival and chemoresistance
    Guerreiro, Ana
    Fattet, Sarah
    Grabowska, Dorota
    Elsing, Alexandra
    Shalaby, Tarek
    Jackson, Shaun
    Schoenwaelder, Simone
    Grotzer, Michael
    Delattre, Olivier
    Arcaro, Alexandre
    [J]. CANCER RESEARCH, 2009, 69
  • [4] A Sensitized RNA Interference Screen Identifies a Novel Role for the PI3K p110γ Isoform in Medulloblastoma Cell Proliferation and Chemoresistance
    Guerreiro, Ana S.
    Fattet, Sarah
    Kulesza, Dorota W.
    Atamer, Abdullah
    Elsing, Alexandra N.
    Shalaby, Tarek
    Jackson, Shaun P.
    Schoenwaelder, Simone M.
    Grotzer, Michael A.
    Delattre, Olivier
    Arcaro, Alexandre
    [J]. MOLECULAR CANCER RESEARCH, 2011, 9 (07) : 925 - 935
  • [5] CO-INHIBITION OF p110α AND p110β IS REQUIRED FOR SUSTAINED PI3K SUPPRESSION
    不详
    [J]. CANCER DISCOVERY, 2015, 5 (02) : 105 - 105
  • [6] Non-redundant involvement of the PI3K isoforms p110γ and p110δ in the development and survival of myeloid cells
    Bucher, Kirsten
    Schmitt, Fee
    Autenrieth, Stella
    Nuernberg, Bernd
    Beer-Hammer, Sandra
    [J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2014, 387 : S32 - S32
  • [7] Human tumor mutants in the p110α subunit of PI3K
    Liu, Zhenning
    Roberts, Thomas M.
    [J]. CELL CYCLE, 2006, 5 (07) : 675 - 677
  • [8] Inhibition of Vps34 and p110δ PI3K Impairs Migration, Invasion and Three-Dimensional Spheroid Growth in Breast Cancer Cells
    Di Donato, Marzia
    Giovannelli, Pia
    Migliaccio, Antimo
    Bilancio, Antonio
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (16)
  • [9] Comparing the Roles of the p110α and p110β Isoforms of PI3K in Signaling and Cancer
    Ilic, Nina
    Roberts, Thomas M.
    [J]. PHOSPHOINOSITIDE 3-KINASE IN HEALTH AND DISEASE, VOL 2, 2011, 347 : 55 - 77
  • [10] Is PI3K p110δ Expressed and Functional in Merkel Cell Carcinoma?
    Chteinberg, Emil
    Rennspiess, Dorit
    Winnepenninckx, Veronique
    Speel, Ernst-Jan
    Kurz, Anna Kordelia
    Zenke, Martin
    zur Hausen, Axel
    [J]. MODERN PATHOLOGY, 2018, 31 : 196 - 197