Resolution enhancement of overlapped peaks of ion mobility spectrometry based on stationary wavelet transform

Lack of sufficient resolving power is one common problem in quantitative determination using ion mobility spectrometry (IMS) method. This paper proposes a new application of stationary wavelet transform (SWT) in resolving the overlapped peaks in IMS. Firstly, the ion product overlapped peaks are denoised by wavelet transform and secondly, the overlapping peaks are resolved by looking into coefficients of SWT. One- and two-component overlapping ion peaks of IMS are processed with the developed SWT method, which yields the significant improvement of resolution. Lack of sufficient resolving power is one common problem in quantitative determination using ion mobility spectrometry (IMS) method. This paper proposes a new application of stationary wavelet transform (SWT) in resolving the overlapped peaks in IMS. Firstly, the ion product overlapped peaks are denoised by wavelet transform and secondly, the overlapping peaks are resolved by looking into coefficients of SWT. One- and two-component overlapping ion peaks of IMS are processed with the developed SWT method, which yields the significant improvement of resolution.