Mass Spectrometry in Wastewater-Based Epidemiology for the Determination of Small and Large Molecules as Biomarkers of Exposure: Toward a Global View of Environment and Human Health under the COVID-19 Outbreak

被引：11

作者：

Pico, Yolanda ^{[1
]}

Barcelo, Damia ^{[2
,3
]}

机构：

[1] Univ Valencia SAMA UV, Environm & Food Safety Res Grp, Desertificat Res Ctr CIDE, Joint Ctr CSIC,Generalitat Valencia, Valencia 46113, Spain

[2] IDAEA CSIC, Dept Environm Chem, Water & Soil Qual Res Grp, Barcelona 08034, Spain

[3] Univ Girona, Catalan Inst Water Res ICRA CERCA, Technol Pk, Girona 17003, Spain

来源：

ACS OMEGA | 2021年 / 6卷 / 46期

关键词：

PSYCHOACTIVE SUBSTANCES;

D O I：

10.1021/acsomega.1c04362

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Wastewater-based epidemiology (WBE) estimates collective consumption or exposure to chemicals or pathogens by monitoring the substances excreted in the population's wastewater. Advances in mass spectrometry (MS) and the application of some clinical diagnostic tools and proteomics to wastewater fingerprinting have been linked to the discovery of new biomarkers and indicators of population health and are broadening the scope of WBE that nowadays cover not only small molecule biomarkers but also genetic biomarkers, large molecules, viruses, infection diseases, resistance, etc. This mini-review highlights recent WBE advances using MS and how this progress can create a fingerprint of a city's health hazards, habits, and lifestyle, which is gaining in public health emphasis.

引用

页码：30865 / 30872

页数：8