The effect of local application of mitomycin-C on the development of capsule around silicone implants in the breast: An experimental study in mice

被引：31
|
作者：
Frangou, J
Kanellaki, M
机构：
[1] Thessaloniki,
[2] Greece,undefined
来源：
AESTHETIC PLASTIC SURGERY | 2001年 / 25卷 / 02期
关键词：
breast implant; capsural contracture; mitomycin-C;
D O I：
10.1007/s002660010108
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
In this experimental study on mice we try to prove that capsule formation around breast implants is considerably diminished after topical application of Mitomycin-C (MMC). MMC solution is applied under the breast tissue or pectoralis major muscle, in the pocket of the silicone implant and just before placing it. This is a morphological study of the connective tissue formed around the implant, under light and electron microscope. Our results suggest that it is worthwhile working on a clinical study trying to prevent the most common complication of breast implants, contracture of a capsule.
引用
收藏
页码：118 / 128
页数：11
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