Decreasing hemoglobin oxygen affinity with inositol tripyrophosphate (itpp) increases maximal exercise capacity in mice with severe heart failure

被引:0
|
作者
Bolo, Andreia [1 ]
Greferath, Ruth [2 ]
Siwik, Deborah [1 ]
Schwarz, Richard [2 ]
Lehn, Jean-Marie [3 ]
Nicolau, Claude [2 ]
Colucci, Wilson S. [1 ]
机构
[1] Boston Univ, Boston, MA 02215 USA
[2] Oxypius Inc, Medford, MA USA
[3] Univ Strasbourg 1, Strasbourg, France
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1885
引用
收藏
页码:404 / 404
页数:1
相关论文
共 19 条
  • [1] Reduction of hemoglobin-oxygen affinity improves exercise capacity in mice with chronic heart failure
    Hikoso, Shungo
    Watanabe, Tetsuya
    Otsu, Kinya
    Hori, Masatsugu
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2007, 42 : S150 - S150
  • [2] Reduction of hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure
    Watanabe, Tetsuya
    Otsu, Kinya
    Higuchi, Yoshiharu
    Yamaguchi, Osamu
    Hikoso, Syungo
    Takeda, Toshihiro
    Shimizu, Takahiko
    Nishida, Kazuhiko
    Imai, Kiyohiro
    Shirasawa, Takuji
    Hori, Masatsugu
    CIRCULATION, 2006, 114 (18) : 12 - 12
  • [3] REDUCTION IN HEMOGLOBIN-OXYGEN AFFINITY RESULTS IN THE IMPROVEMENT OF EXERCISE CAPACITY IN MICE WITH CHRONIC HEART FAILURE
    Takeda, Toshihiro
    Watanabe, Tetsuya
    Omiya, Shigemiki
    Otsu, Kinya
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 315 - 315
  • [4] Reduction in Hemoglobin-Oxygen Affinity Results in the Improvement of Exercise Capacity in Mice with Chronic Heart Failure
    Takeda, Toshihiro
    Watanebe, Tetsuya
    Omiya, Shigemiki
    Otsu, Kinya
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2008, 45 : S8 - S9
  • [5] Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure
    Watanabe, Tetsuya
    Takeda, Toshihiro
    Omiya, Shigemiki
    Hikoso, Shungo
    Yamaguchi, Osamu
    Nakano, Yuko
    Higuchi, Yoshiharu
    Nakai, Atsuko
    Abe, Yusuke
    Aki-Jin, Yayoi
    Taniike, Masayuki
    Mizote, Isamu
    Matsumura, Yasushi
    Shimizu, Takahiko
    Nishida, Kazuhiko
    Imai, Kiyohiro
    Hori, Masatsugu
    Shirasawa, Takuji
    Otsu, Kinya
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (09) : 779 - 786
  • [6] Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate
    Biolo, Andreia
    Greferath, Ruth
    Siwik, Deborah A.
    Qin, Fuzhong
    Valsky, Eugene
    Fylaktakidou, Konstantina C.
    Pothukanuri, Srinivasu
    Duarte, Carolina D.
    Schwarz, Richard P.
    Lehn, Jean-Marie
    Nicolau, Claude
    Colucci, Wilson S.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (06) : 1926 - 1929
  • [7] Isolated Quadriceps Training Increases Maximal Exercise Capacity in Chronic Heart Failure The Role of Skeletal Muscle Convective and Diffusive Oxygen Transport
    Esposito, Fabio
    Reese, Van
    Shabetai, Ralph
    Wagner, Peter D.
    Richardson, Russell S.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 58 (13) : 1353 - 1362
  • [8] Lack of effect of increased inspired oxygen concentrations on maximal exercise capacity or ventilation in stable heart failure
    Russell, SD
    Koshkarian, GM
    Medinger, AE
    Carson, PE
    Higginbotham, MB
    AMERICAN JOURNAL OF CARDIOLOGY, 1999, 84 (12): : 1412 - 1416
  • [9] Role of the etiology of cardiomyopathies on exercise capacity and oxygen consumption in patients with severe congestive heart failure
    Juillière, Y
    Grentzinger, A
    Houplon, P
    Démoulin, S
    Berder, V
    Suty-Selton, C
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2000, 73 (03) : 251 - 255
  • [10] Domiciliary oxygen therapy improves sub-maximal exercise capacity and quality of life in chronic heart failure
    Paul, Biju
    Joseph, Majo
    De Pasquale, Carmine G.
    HEART LUNG AND CIRCULATION, 2008, 17 (03): : 220 - 223