A multi-institutional initiative on patient-related quality assurance: Independent computational dose verification of fluence-modulated treatment techniques

被引：1

作者：

Teichmann, Tobias ^{[1
]}

Salz, Henning ^{[1
,11
]}

Schwedas, Michael ^{[1
]}

Schilz, Johannes ^{[2
]}

Wolf, Ulrich ^{[3
]}

Walke, Mathias ^{[4
]}

Kornhuber, Christine ^{[5
]}

Berger, Rene ^{[6
]}

Schroeder, Dirk ^{[7
]}

Hourle, Marcus ^{[8
]}

Peil, Torsten ^{[9
]}

Tuemmler, Heiko ^{[10
]}

Wiezorek, Tilo ^{[1
]}

Wittig, Andrea ^{[1
]}

机构：

[1] Univ Hosp Jena, Dept Radiat Oncol, Bachstr 18, D-07743 Jena, Germany

[2] Helios Hosp Erfurt, Dept Radiat Oncol, Nordhauser Str 74, D-99089 Erfurt, Germany

[3] Univ Hosp Leipzig, Dept Radiat Oncol, Stephanstr 9a, D-04103 Leipzig, Germany

[4] Otto von Guericke Univ, Dept Radiat Oncol, Leipziger Str 44, D-39120 Magdeburg, Germany

[5] Univ Hosp Halle, Dept Radiat Oncol, Ernst Grube Str 40, D-06120 Halle, Saale, Germany

[6] SRH Hosp Gera, Dept Radiat Oncol, Str Friedens 122, D-07548 Gera, Germany

[7] SRH Cent Hosp Suhl, Dept Radiat Oncol, Albert Schweitzer Str 2, D-98527 Suhl, Germany

[8] Hosp Chemnitz, Dept Radiat Oncol, Burgerstr 2, D-09113 Chemnitz, Germany

[9] MVZ Ctr Radiat Oncol Halle GmbH, Niemeyerstrae 24, D-06110 Halle, Saale, Germany

[10] Community Hosp Dresden Friedrichstadt, Dept Radiat Oncol, Friedrichstr 41, D-01067 Dresden, Germany

[11] Cyberknife Ctr Mitteldeutschland, Dept Radiosurg & High Precis Robot Treatments, Nordhauserstr 74, D-99089 Erfurt, Germany

来源：

ZEITSCHRIFT FUR MEDIZINISCHE PHYSIK | 2020年 / 30卷 / 02期

关键词：

Computational dose verification; Fluence-modulated Mobius3D; Multi-institutional initiative; IMRT; CONVOLUTION; SYSTEM;

D O I：

10.1016/j.zemedi.2019.12.003

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: This multi-institutional study investigates whether computational verification of fluence-modulated treatment plans using independent software with its own Strahlerkopfmodel is an appropriate method for patient-related quality assurance (PRQA) in the context of various combinations of linear accelerators (linacs), treatment techniques and treatment planning systems (TPS). Materials and methods: The PRQA-software's (Mobius3D) recalculations of 9 institutions' treatment plans were analyzed for a horseshoe-shaped planning target volume (PTV) inside a phantom. The recomputed dose distributions were compared to a) the dose distributions as calculated by all TPS's and b) the measured dose distributions, which were acquired using the same independent measuring system for all institutions. Furthermore, dose volume histograms were examined. The penumbra deviations and mean gamma values were quantified using Verisoft (PTW). Additionally workflow requirements for computational verification were discussed. Results: Mobius3D is compatible with all examined TPSs, treatment techniques and linacs. The mean PTV dose differences (Mobius3D-TPS, <3.0%) and 3D gamma passing rates (>95.0%) led to a positive plan acceptance result in all cases. These results are similar to the outcome of the dosimetric measurements with one exception. The mean gamma values (<0.5) show a good agreement between Mobius3D and the TPS dose distributions. Conclusion: Using Mobius3D was proven to be an appropriate computational PRQA method for the tested combinations of linacs, treatment techniques and TPS's. The clinical use of Mobius3D has to be complemented with regular dosimetric measurements and thorough linac and TPS QA. Mobius3D 's computational verification reduced measurement effort and personnel needs in comparison to dosimetric verifications.

引用

页码：155 / 165

页数：11

共 2 条

[1] Patient-related quality assurance with different combinations of treatment planning systems, techniques, and machines
Steiniger, Beatrice
Berger, Rene
Eilzer, Sabine
Kornhuber, Christine
Lorenz, Kathleen
Peil, Torsten
Reiffenstuhl, Carsten
Schilz, Johannes
Schroeder, Dirk
Schwedas, Michael
Pensold, Stephanie
Walke, Mathias
Weibert, Kirsten
Wolf, Ulrich
Wiezorek, Tilo
STRAHLENTHERAPIE UND ONKOLOGIE, 2017, 193 (01) : 46 - 54
[2] Patient-related quality assurance with different combinations of treatment planning systems, techniques, and machines: A multi-institutional survey; [Patientenbezogene Qualitätssicherung mit unterschiedlichen Kombinationen von Planungssystemen, Techniken und Geräten: Eine multiinstitutionelle Studie]
Steiniger B.
Berger R.
Eilzer S.
Kornhuber C.
Lorenz K.
Peil T.
Reiffenstuhl C.
Schilz J.
Schröder D.
Schwedas M.
Pensold S.
Walke M.
Weibert K.
Wolf U.
Wiezorek T.
Strahlentherapie und Onkologie, 2017, 193 (1) : 46 - 54

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