Infiltrating leukocytes surround early Buruli ulcer lesions, but are unable to reach the mycolactone producing mycobacteria

被引:19
|
作者
Ruf, Marie-Therese [1 ,2 ]
Steffen, Christina [3 ]
Bolz, Miriam [1 ,2 ,4 ]
Schmid, Peter [1 ,2 ]
Pluschke, Gerd [1 ,2 ]
机构
[1] Swiss Trop & Publ Hlth Inst, Basel, Switzerland
[2] Univ Basel, Basel, Switzerland
[3] Cairns Hosp, Dept Surg, Cairns, Qld, Australia
[4] NYU, Sch Med, Dept Med, Div Infect Dis & Immunol, New York, NY USA
关键词
buruli ulcer; early pathogenesis; histopathology; infiltration; mycobacterium ulcerans; mycolactone; HOST IMMUNE-RESPONSE; CYTOKINE PRODUCTION; TOXIN MYCOLACTONE; INFECTION; VICTORIA; CHEMOTHERAPY; INHIBITION; AUSTRALIA; MACROLIDE; VIRULENCE;
D O I
10.1080/21505594.2017.1370530
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:1918 / 1926
页数:9
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