Metformin attenuates CagA-positive Helicobacter pylori-induced gastric cancer stem-like cell phenotype mediated by CDX1 suppression

被引:0
|
作者
Choi, S. [1 ]
Yoon, C. [2 ]
Park, M. [1 ]
Lee, D. [1 ]
Hong, K. [1 ]
Ashktorab, H. [3 ]
Smoot, D. [3 ]
Cho, S. [1 ]
机构
[1] Natl Canc Ctr, Goyang, Gyeonggi, South Korea
[2] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[3] Howard Univ, Washington, DC 20059 USA
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
W4.2
引用
收藏
页数:1
相关论文
共 22 条
  • [1] Metformin attenuates CagA-positive Helicobacter pylori-induced gastric cancer stem-like cell phenotype mediated by CDX1 suppression
    Choi, Sang Il
    Yoon, Changhwan
    Park, Mi Ree
    Lee, Dahyung
    Hong, Kyoung-Ok
    Ashktorab, Hassan
    Smoot, Duane T.
    Cho, Soo-Jeong
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2018, 33 : 50 - 50
  • [2] CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis
    Choi, Sang Il
    Yoon, Changhwan
    Park, Mi Ree
    Lee, DaHyung
    Kook, Myeong-Cherl
    Lin, Jian-Xian
    Kang, Jun Hyuk
    Ashktorab, Hassan
    Smoot, Duane T.
    Yoon, Sam S.
    Cho, Soo-Jeong
    MOLECULAR CANCER RESEARCH, 2019, 17 (11) : 2169 - 2183
  • [3] RETRACTION: CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis
    Choi, Sang Il
    Yoon, Changhwan
    Park, Mi Ree
    Lee, DaHyung
    Kook, Myeong-Cherl
    Lin, Jian-Xian
    Kang, Jun Hyuk
    Ashktorab, Hassan
    Smoot, Duane T.
    Yoon, Sam S.
    Cho, Soo-Jeong
    MOLECULAR CANCER RESEARCH, 2024, 22 (11) : 1065 - 1065
  • [4] Evaluation of the virulence of CagA-positive Helicobacter pylori with mouse embryonic stem cell-derived gastric organoid
    Hashi, Kana
    Hatakeyama, Masanori
    CANCER SCIENCE, 2018, 109 : 54 - 54
  • [5] Chronic CagA-positive Helicobacter pylori infection with MNNG stimulation synergistically induces mesenchymal and cancer stem cell-like properties in gastric mucosal epithelial cells
    Lin, Li
    Wei, Hulai
    Yi, Juan
    Xie, Bei
    Chen, Jing
    Zhou, Cunmin
    Wang, Li
    Yang, Yue
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 120 (10) : 17635 - 17649
  • [6] Reactive Oxygen Species-Induced Autophagic Degradation of Helicobacter pylori CagA Is Specifically Suppressed in Cancer Stem-like Cells
    Tsugawa, Hitoshi
    Suzuki, Hidekazu
    Saya, Hideyuki
    Hatakeyama, Masanori
    Hirayama, Toshiya
    Hirata, Kenro
    Nagano, Osamu
    Matsuzaki, Juntaro
    Hibi, Toshifumi
    CELL HOST & MICROBE, 2012, 12 (06) : 764 - 777
  • [7] Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro
    Bessede, Emilie
    Molina, Silvia
    Amador, Luis Acuna
    Dubus, Pierre
    Staedel, Cathy
    Chambonnier, Lucie
    Buissonniere, Alice
    Sifre, Elodie
    Giese, Alban
    Benejat, Lucie
    Rousseau, Benoit
    Costet, Pierre
    Sacks, David B.
    Megraud, Francis
    Varon, Christine
    ONCOTARGET, 2016, 7 (49) : 80688 - 80699
  • [8] Suppression of Helicobacter pylori-induced interleukin-8 production in gastric cancer cell lines by an anti-ulcer drug, geranylgeranylacetone
    Yoshimura, N
    Suzuki, Y
    Saito, Y
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2002, 17 (11) : 1153 - 1160
  • [9] Helicobacter pylori CagA protein induces gastric cancer stem cell-like properties through the Akt/FOXO3a axis
    Chen, Zheng-wei
    Dong, Zhe-bin
    Xiang, Han-ting
    Chen, Sang-sang
    Yu, Wei-ming
    Liang, Chao
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2024, 125 (03)
  • [10] Gastric coinfection with thiopeptide-positive Cutibacterium acnes decreases FOXM1 and pro-inflammatory biomarker expression in a murine model of Helicobacter pylori-induced gastric cancer
    Lunger, Courtney
    Shen, Zeli
    Holcombe, Hilda
    Mannion, Anthony J.
    Dzink-Fox, JoAnn
    Kurnick, Susanna
    Feng, Yan
    Muthupalani, Sureshkumar
    Carrasco, Sebastian E.
    Wilson, Keith T.
    Peek, Richard M.
    Piazuelo, M. Blanca
    Morgan, Douglas R.
    Armijo, Amanda L.
    Mammoliti, Melissa
    Wang, Timothy C.
    Fox, James G.
    MICROBIOLOGY SPECTRUM, 2024, 12 (01):