Syntheses of the macrocyclic spermine alkaloids (±)-budmunchiamine A-C

被引：0
|
作者：
Popaj, K [1 ]
Hesse, M [1 ]
机构：
[1] Univ Zurich, Inst Organ Chem, CH-8057 Zurich, Switzerland
来源：
HELVETICA CHIMICA ACTA | 2001年 / 84卷 / 01期
关键词：
D O I：
10.1002/1522-2675(20010131)84:1<180::AID-HLCA180>3.0.CO;2-F
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The syntheses of four macrocyclic spermine alkaloids, (+/-)-budmunchiamine A-C (la-c) and (+/-)-budmunchiamine L4 (1), were accomplished by Michael addition of spermine to the ag-unsaturated esters 3a-d, followed by cyclization of the resulting alpha,omega -tetraamino esters 4a-d with triethoxyantimony; N-methylation of the amino lactams 6a-c yielded the budmunchiamines A-C (la-c).
引用
收藏
页码：180 / 186
页数：7
相关论文
共 50 条
12345