Early neonatal brain injury in histologic chorioamnionitis

被引:118
|
作者
De Felice, C
Toti, P
Laurini, RN
Stumpo, M
Picciolini, E
Todros, T
Tanganelli, P
Buonocore, G
Bracci, R
机构
[1] Univ Siena, Dept Prevent Pediat & Neonatol, I-53100 Siena, Italy
[2] Univ Siena, Inst Pathol, I-53100 Siena, Italy
[3] Univ Siena, Dept Obstet & Gynecol, I-53100 Siena, Italy
[4] Univ Turin, Div Fetomaternal Med, Turin, Italy
[5] Univ Lausanne, Div Dev Pathol, Lausanne, Switzerland
来源
JOURNAL OF PEDIATRICS | 2001年 / 138卷 / 01期
关键词
D O I
10.1067/mpd.2001.109605
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The relation between clinical or histologic chorioamnionitis and early neonatal adverse neurologic outcome was investigated (n = 483). Histologic, but not clinical, evidence of chorioamnionitis was found to be a significant predictor of per;ventricular echodensity (odds ratio, 2.4; 95% CI, 1.8-3.2), echolucency (3.3; 1.9-5.6), ventriculomegaly (2.7; 1.8-4.2), intraventricular hemorrhage greater than or equal to3 (3.5; 2.4-5.2), and seizures (2.3; 1.4-3.7).
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页码:101 / 104
页数:4
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