Anti-NMDA Receptor Encephalitis Presenting with Acute Psychosis

Autoimmune encephalitis cases are diagnosed more frequently with the increase in the number of investigative facilities and the raising awareness of clinicians. Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is the most common type of autoimmune encephalitis in childhood. Early diagnosis of the disease contributes significantly to prognosis. Diagnosis is made by detecting antibodies against anti-NMDA receptors in the cerebrospinal fluid (CSF) and serum. Central nervous system imaging and electroencephalography (EEG) findings are not specific to the disease and may have supportive role in diagnosis. Herein, we report a 15 year-old-girl who presented with fever, psychotic symptoms and unconsciousness and was diagnosed with anti-NMDA receptor encephalitis.