c-maf in multiple myeloma:: An oncogene enhancing tumor-stroma interactions

被引：21

作者：

Kienast, J ^{[1
]}

Berdel, WE ^{[1
]}

机构：

[1] Univ Munster, Dept Med Hematol & Oncol, D-48129 Munster, Germany

来源：

CANCER CELL | 2004年 / 5卷 / 02期

关键词：

D O I：

10.1016/S1535-6108(04)00030-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Gene expression profiling studies reported by Hurt et al. in this issue of Cancer Cell reveal an unexpectedly frequent overexpression of c-maf in multiple myeloma and identify molecular targets of c-maf transactivation. The results define c-maf as a prototype of a class of oncogenes that not only stimulate cell cycle progression, but also promote pathological interactions between tumor and stroma cells.

引用

页码：109 / 110

页数：2

共 50 条

[1] c-maf oncogene dysregulation in multiple myeloma: Frequency and biological relevance
Rasmussen, T
Knudsen, LM
Dahl, IMS
Johnsen, HE
LEUKEMIA & LYMPHOMA, 2003, 44 (10) : 1761 - 1766
[2] Evolutionary Dynamics of Tumor-Stroma Interactions in Multiple Myeloma
Sartakhti, Javad Salimi
Manshaei, Mohammad Hossein
Bateni, Soroosh
Archetti, Marco
PLOS ONE, 2016, 11 (12):
[3] The oncogene c-maf is upregulated by a MEK/ERK-dependent mechanism in multiple myeloma
Annunziata, C. M.
Davis, R. E.
Lam, L. T.
Hurt, E. M.
Shaffer, A. L.
Staudt, L. M.
ANNALS OF ONCOLOGY, 2008, 19 : 25 - 25
[4] Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma
Hurt, EM
Wiestner, A
Rosenwald, A
Shaffer, AL
Campo, E
Grogan, T
Bergsagel, PL
Kuehl, WM
Staudt, LM
CANCER CELL, 2004, 5 (02) : 191 - 199
[5] Atypical IgM multiple myeloma with deletion of c-MAF
Juarez Salcedo, L. M.
Lopez Rubio, M.
Gil Fernandez, J. J.
Garcia-Suarez, J.
Magro, E.
Arranz, E.
Gutierrez Jomarron, I.
Marcellini Antonio, S.
Blasco, A.
Burgaleta, C.
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2015, 37 (05) : 686 - 689
[6] Understanding the modulation of c-Maf stability in multiple myeloma
Science Foundation in China, 2016, (02) : 28 - 28
[7] Tumor-stroma interactions
Bhowmick, NA
Moses, HL
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2005, 15 (01) : 97 - 101
[8] Tumor-stroma interactions
Billottet, Clotilde
Jouanneau, Jacqueline
BULLETIN DU CANCER, 2008, 95 (01) : 51 - 56
[9] Tumor-Stroma interactions
Kiaris, Hippokratis
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2010, 21 (01) : 1 - 1
[10] c-Maf nuclear oncoprotein is frequently expressed in multiple myeloma
Chang, Hong
Qi, Q.
Xu, W.
Patterson, B.
LEUKEMIA, 2007, 21 (07) : 1572 - 1574

← 1 2 3 4 5 →