Quantitation of 14-3-3 and neuron-specific enolase proteins in CSF in Creutzfeldt-Jakob disease

被引：61
|
作者：
Aksamit, AJ
Preissner, CM
Homburger, HA
机构：
[1] Mayo Clin, Dept Neurol, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Lab Med & Pathol, Rochester, MN 55905 USA
来源：
NEUROLOGY | 2001年 / 57卷 / 04期
关键词：
D O I：
10.1212/WNL.57.4.728
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
CSF 14-3-3 and neuron-specific enolase (NSE) proteins were quantitated from patients who had Creutzfeldt-Jakob disease (CJD) or other rapidly dementing disorders initially considered to be CJD. Thirty-one patients were diagnosed as having CJD among 152 studied. CSF 14-3-3 values more than 8 ng/mL correlated with CJD. CSF NSE values less than 30 ng/mL and 14-3-3 values less than 8 ng/mL made a diagnosis of CJD unlikely, but did not exclude it.
引用
收藏
页码：728 / 730
页数：3
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