Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats

被引:79
|
作者
Kenny, PJ [1 ]
Paterson, NE [1 ]
Boutrel, B [1 ]
Semenova, S [1 ]
Harrison, A [1 ]
Gasparini, F [1 ]
Koob, GF [1 ]
Skoubis, PD [1 ]
Markou, A [1 ]
机构
[1] Scripps Res Inst, Dept Neuropharmacol, La Jolla, CA 92037 USA
关键词
cocaine; nicotine; glutamate; self-administration; intracranial self-stimulation;
D O I
10.1196/annals.1300.040
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:415 / 418
页数:4
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