Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

被引：29

作者：

Majors, Catherine E. ^{[1
]}

Smith, Chelsey A. ^{[1
]}

Natoli, Mary E. ^{[1
]}

Kundrod, Kathryn A. ^{[1
]}

Richards-Kortum, Rebecca ^{[1
]}

机构：

[1] Rice Univ, Dept Bioengn, 6100 Main St,MS 142, Houston, TX 77005 USA

来源：

LAB ON A CHIP | 2017年 / 17卷 / 20期

基金：

美国国家卫生研究院;

关键词：

C-REACTIVE PROTEIN; RECOMBINASE POLYMERASE AMPLIFICATION; GESTATIONAL DIABETES-MELLITUS; FACTOR BINDING PROTEIN-1; BLOOD-PRESSURE DEVICE; HIV-INFECTED PATIENTS; LATERAL FLOW ASSAY; REAL-TIME PCR; PREMATURE RUPTURE; LOW-COST;

D O I：

10.1039/c7lc00374a

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Each day, approximately 830 women and 7400 newborns die from complications during pregnancy and childbirth. Improving maternal and neonatal health will require bringing rapid diagnosis and treatment to the point of care in low-resource settings. However, to date there are few diagnostic tools available that can be used at the point of care to detect the leading causes of maternal and neonatal mortality in low-resource settings. Here we review both commercially available diagnostics and technologies that are currently in development to detect the leading causes of maternal and neonatal mortality, highlighting key gaps in development where innovative design could increase access to technology and enable rapid diagnosis at the bedside.

引用

页码：3351 / 3387

页数：37

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