Colloidal Drug Delivery Systems: Current Status and Future Directions

被引:26
|
作者
Garg, Tarun [1 ]
Rath, Goutam
Goyal, Annit K.
机构
[1] ISF Coll Pharm, Dept Pharmaceut, Moga, Punjab, India
关键词
Vesicular drug delivery; particulate drug delivery; liposomes; niosomes; cell delivery; resealed erythrocytes; GINKGO-BILOBA PHYTOSOMES; MONOPHOSPHORYL-LIPID-A; WATER-SOLUBLE DRUG; IN-VITRO RELEASE; IMMUNOSTIMULATING COMPLEXES ISCOMS; LIQUID-CRYSTALLINE NANOPARTICLES; OVERCOME MULTIDRUG-RESISTANCE; ENHANCED ORAL BIOAVAILABILITY; POLYMERIC MIXED MICELLES; VIRUS-LIKE PARTICLES;
D O I
10.1615/CritRevTherDrugCarrierSyst.2015010159
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In this paper, we provide an overview an extensive range of colloidal drug delivery systems with special focus on vesicular and particulates systems that are being used in research or might be potentially useful as carriers systems for drug or active biomolecules or as cell carriers with application in the therapeutic field. We present some important examples of commercially available drug delivery systems with applications in research or in clinical fields. This class of systems is widely used due to excellent drug targeting, sustained and controlled release behavior, higher entrapment efficiency of drug molecules, prevention of drug hydrolysis or enzymatic degradation, and improvement of therapeutic efficacy. These characteristics help in the selection of suitable carrier systems for drug, cell, and gene delivery in different fields.
引用
收藏
页码:89 / 147
页数:59
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