ANTICANCER ACTIVITY OF POLYHERBAL FORMULATION AGAINST HUMAN BLOOD CANCER CELLS

被引：0

作者：

Sujithra, M. ^{[1
]}

Devi, Nirmala ^{[1
]}

Sathish, S. ^{[1
]}

Oviya, M. ^{[1
]}

机构：

[1] Dhanalakshmisrinivasan Coll Arts & Sci Women Auto, Perambalur, India

来源：

INTERNATIONAL JOURNAL OF LIFE SCIENCE AND PHARMA RESEARCH | 2021年

关键词：

Anti-cancer; Polyherbal formulation; phytochemical; MOLT-4; cells; Ficusreligiosa; Allium sativum; GOLD NANOPARTICLES; MULTIPLE-MYELOMA; HODGKIN LYMPHOMA; ABLATION; LEUKEMIA; DNA;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The Ficusreligiosa, Album sativum, Sennaauriculata, Andrographispaniculata, Momordicacharantia and Eugenia jambolana, are well-known plants available throughout India and they are commonly used for the treatment of various diseases. The polyherbal formulation was formulated using the hydroalcoholic extracts of the Ficusreligiosa, Album sativum, Sennaauriculata, Andrographispaniculata, Momordicacharantia, Eugenia jambolanaby the Soxhlet extraction method. The phytochemical characterization was carried out for the polyherbal formulation. Further, the anticancer activity of polyherbal formulation was studied using MOLT-4 cells and their mechanism of action was analyzed by ETBr/AO staining method. The ETBr/AO staining results further confirmed the polyherbal formulation. Taken together, these results showed thatthe polyherbal formulation has anti-cancer potential and can be used for the treatment of blood cancer.

引用

页码：231 / 236

页数：6

共 50 条

[1] Manzamine A Exerts Anticancer Activity against Human Colorectal Cancer Cells
Lin, Li-Chun
Kuo, Tzu-Ting
Chang, Hsin-Yi
Liu, Wen-Shan
Hsia, Shih-Min
Huang, Tsui-Chin
[J]. MARINE DRUGS, 2018, 16 (08)
[2] Cellular mechanisms mediating the anticancer activity of a novel polyherbal formulation.
Shraibom, Nadav Menahem
Jaggi, Manu
Singh, Anu T.
Verma, Ritu
Madaan, Alka
Singh, Pratibha
Awasthi, Anshumali
Joshi, Vidushi
Kishore, Amitesh
Dobhal, Sheetal
Kar, Ronodip
Meena, Kalpana
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
[3] Antiinflammatory Activity of a Polyherbal Formulation
Deorukhakar, S. R.
Dethe, A.
Vohra, R. R.
Ghosh, R.
Chaudhary, J.
Kadam, V.
[J]. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2008, 70 (06) : 785 - 787
[4] In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells
Sharma, Vikas
Hussain, Shabir
Gupta, Moni
Saxena, Ajit Kumar
[J]. INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS, 2014, 51 (05): : 416 - 419
[5] Novel Anticancer Activity of the Autocleaved Ovotransferrin against Human Colon and Breast Cancer Cells
Ibrahim, Hisham R.
Kiyono, Tohru
[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (23) : 11383 - 11390
[6] Anticancer activity of okra raw polysaccharides extracts against human liver cancer cells
Hayaza, Suhailah
Wahyuningsih, Sri Puji Astuti
Susilo, Raden Joko Kuncoroningrat
Permanasari, Adita Ayu
Husen, Saikhu Akhmad
Winarni, Dwi
Punnapayak, Hunsa
Darmanto, Win
[J]. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2019, 18 (08) : 1667 - 1672
[7] Differential Anticancer Activity of Pterostilbene Against Three Subtypes of Human Breast Cancer Cells
Wakimoto, Rei
Ono, Misaki
Takeshima, Mikako
Higuchi, Takako
Nakano, Shuji
[J]. ANTICANCER RESEARCH, 2017, 37 (11) : 6153 - 6159
[8] Anticancer activity of a novel histone deacetylase inhibitor against human colorectal cancer cells
Campostrini, N.
Cecconi, D.
Mill, A.
Vindigni, A.
Bossi, A.
Righetti, P. G.
[J]. MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (10) : S97 - S97
[9] Anticancer Activity of Thymoquinone Cubic Phase Nanoparticles Against Human Breast Cancer: Formulation, Cytotoxicity and Subcellular Localization
Mehanna, Mohammed M.
Sarieddine, Rana
Alwattar, Jana K.
Chouaib, Racha
Gali-Muhtasib, Hala
[J]. INTERNATIONAL JOURNAL OF NANOMEDICINE, 2020, 15 : 9557 - 9570
[10] Antimicrobial activity of a polyherbal formulation Ambrex
Raslin, Anila
Rajkumar, Johanna
[J]. INTERNATIONAL JOURNAL OF MATERIALS & PRODUCT TECHNOLOGY, 2017, 55 (1-3): : 286 - 295

← 1 2 3 4 5 →