Nonlinear interferometric vibrational imaging of biological tissue

被引：1

作者：

Jiang, Zhi ^{[1
]}

Marks, Daniel L. ^{[1
]}

Geddes, Joseph B., III ^{[1
]}

Boppart, Stephen A. ^{[1
]}

机构：

[1] Univ Illinois, Biophoton Imaging Lab, Beckman Inst Adv Sci & Technol, Urbana, IL 61801 USA

来源：

MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES VIII | 2008年 / 6860卷

关键词：

coherent anti-Stokes Raman scattering; nonlinear microscopy; biomedical imaging;

D O I：

10.1117/12.763306

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We demonstrate imaging with the technique of nonlinear interferometric vibrational imaging (NIVI). Experimental images using this instrumentation and method have been acquired from both phantom and biological tissues. In our system, coherent anti-Stokes Raman scattering (CARS) signals are detected by spectral interferometry, which is able to fully restore high resolution Raman spectrum on each focal spot of a sample covering multiple Raman bands using broadband pump and Stokes laser beams. Spectral-domain detection has been demonstrated and allows for a significant increase in image acquiring speed, in signal-to-noise, and in interferometric signal stability.

引用

页数：6

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