Temozolomide In Acute Myeloid Leukemia: A MGMT Promoter Methylation Status-Based Treatment Stratification

被引：0
|
作者：
Medeiros, Bruno C.
Kohrt, Holbrook E.
Rajwanshi, Richa
Gotlib, Jason [1 ]
Coutre, Steven
Liedtke, Michaela [1 ]
Berube, Caroline
Zhang, Melody [1 ]
Arber, Daniel A. [2 ]
Zehnder, James L. [3 ]
机构：
[1] Stanford Univ, Sch Med, Div Hematol, Stanford, CA 94305 USA
[2] Stanford Univ, Med Ctr, Dept Clin Lab, Stanford, CA 94305 USA
[3] Stanford Univ, Dept Pathol, Sch Med, Stanford, CA 94305 USA
来源：
BLOOD | 2010年 / 116卷 / 21期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1357 / 1358
页数：2
相关论文
共 50 条
  • [1] Tailored temozolomide therapy according to MGMT methylation status for elderly patients with acute myeloid leukemia
    Medeiros, Bruno C.
    Kohrt, Holbrook E.
    Gotlib, Jason
    Coutre, Steven E.
    Zhang, Bingyang
    Arber, Daniel A.
    Zehnder, James L.
    AMERICAN JOURNAL OF HEMATOLOGY, 2012, 87 (01) : 45 - 50
  • [2] Baseline status of O (6)-methylguanine-DNA-methyltransferase (MGMT) promoter methylation and effect of protracted doses of temozolomide on MGMT in acute leukemia.
    Medeiros, Bruno
    Khan, Sabrina
    Rajwanshi, Richa
    Jones, Carol
    Zehnder, James
    CANCER RESEARCH, 2009, 69
  • [3] Association between the methylation status of the MGMT promoter in bone marrow specimens and chemotherapy outcomes of patients with acute myeloid leukemia
    Hong, Qingxiao
    Chen, Xiaoying
    Ye, Huadan
    Zhou, Annan
    Gao, Yuting
    Jiang, Danjie
    Wu, Xiaodong
    Tian, Bingru
    Chen, Youfen
    Wang, Ming
    Xie, Jiping
    Xia, Yongming
    Duan, Shiwei
    ONCOLOGY LETTERS, 2016, 11 (04) : 2851 - 2856
  • [4] MGMT promoter methylation as a potential prognostic marker for acute leukemia
    Sobieszkoda, Dominika
    Czech, Joanna
    Gablo, Natalia
    Kopanska, Marta
    Tabarkiewicz, Jacek
    Kolacinska, Agnieszka
    Robak, Tadeusz
    Zawlik, Izabela
    ARCHIVES OF MEDICAL SCIENCE, 2017, 13 (06) : 1433 - 1441
  • [5] Methylation status of galectin-12 gene promoter in acute myeloid leukemia
    Helbawi, Fatma M.
    Ahmed, Sohair M.
    Mahmoud, Maged S.
    Assem, Magda M.
    Kamal, Taghreed M.
    Abdou, Madleen Adel A.
    EGYPTIAN JOURNAL OF HAEMATOLOGY, 2021, 46 (01): : 1 - 6
  • [6] Promoter methylation and expression of DNA repair genes hMLH1 and MGMT in acute myeloid leukemia
    Georg Lenz
    Grit Hutter
    Wolfgang Hiddemann
    Martin Dreyling
    Annals of Hematology, 2004, 83 : 628 - 633
  • [7] Promoter methylation and expression of DNA repair genes hMLH1 and MGMT in acute myeloid leukemia
    Lenz, G
    Hutter, G
    Hiddemann, W
    Dreyling, M
    ANNALS OF HEMATOLOGY, 2004, 83 (10) : 628 - 633
  • [8] The Impact of MGMT Promoter Methylation and Temozolomide Treatment in Serbian Patients with Primary Glioblastoma
    Jovanovic, Nikola
    Mitrovic, Tatjana
    Cvetkovic, Vladimir J.
    Tosic, Svetlana
    Vitorovic, Jelena
    Stamenkovic, Slavisa
    Nikolov, Vesna
    Kostic, Aleksandar
    Vidovic, Natasa
    Krstic, Miljan
    Jevtovic-Stoimenov, Tatjana
    Pavlovic, Dusica
    MEDICINA-LITHUANIA, 2019, 55 (02):
  • [9] Personalized treatment strategies in glioblastoma: MGMT promoter methylation status
    Thon, Niklas
    Kreth, Simone
    Kreth, Friedrich-Wilhelm
    ONCOTARGETS AND THERAPY, 2013, 6 : 1363 - 1372
  • [10] Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide
    K A van Nifterik
    J van den Berg
    W F van der Meide
    N Ameziane
    L E Wedekind
    R D M Steenbergen
    S Leenstra
    M V M Lafleur
    B J Slotman
    L J A Stalpers
    P Sminia
    British Journal of Cancer, 2010, 103 : 29 - 35
12345