Biomacromolecule template-based molecularly imprinted polymers with an emphasis on their synthesis strategies: a review

被引:63
|
作者
Zahedi, Payam [1 ]
Ziaee, Morteza [1 ]
Abdouss, Majid [2 ]
Farazin, Alireza [3 ]
Mizaikoff, Boris [4 ]
机构
[1] Univ Tehran, Sch Chem Engn, Coll Engn, Nanobiopolymers Res Lab, POB 11155-4563, Tehran, Iran
[2] Amirkabir Univ Technol, Dept Chem, Tehran Polytech, Tehran, Iran
[3] Univ Tehran, Dept Chem, Fac Sci, Tehran, Iran
[4] Univ Ulm, Inst Analyt & Bioanalyt Chem, D-89081 Ulm, Germany
关键词
molecular imprinted polymers; biomacromolecules; polymerization; core-shell nanoparticles; epitope; FRAGMENTATION CHAIN TRANSFER; LIVING RADICAL POLYMERIZATION; QUARTZ-CRYSTAL MICROBALANCE; ZNS QUANTUM DOTS; RAFT POLYMERIZATION; PROTEIN RECOGNITION; PRECIPITATION POLYMERIZATION; SELECTIVE RECOGNITION; BIOLOGICAL-FLUIDS; RIBONUCLEASE-A;
D O I
10.1002/pat.3754
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Molecular imprinting is an efficient tool for generating synthetic acceptors with specific recognition sites, which are mimed from template structures via polymerization. The final products of this strategy lead to high-performance polymers with active recognition sites for a range of various applications in terms of extraction and separation, characterization and recognition, biomedicine, biosensors, and drug delivery. Molecular imprinting of biomacromolecules synthesizes a series of matrices that may be referred to as biomolecularly imprinted polymers (BMIPs). In this review article, an overview of different methods for fabricating BMIPs with an emphasis on novel polymerization schemes along with potential challenges is discussed. Additionally, selected applications of BMIPs will be briefly highlighted derived from the latest research papers. Copyright (c) 2016 John Wiley & Sons, Ltd.
引用
收藏
页码:1124 / 1142
页数:19
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