Research on Network Model of Dentate Gyrus Based on Bionics

被引:2
|
作者
Zhang, Jin [1 ,2 ]
Wei, Xiaoping [1 ]
Zhang, Shiwen [1 ]
Niu, Xin [3 ]
Li, Guang [4 ]
Tian, Tiantian [5 ]
机构
[1] Hunan Normal Univ, Sch Informat Sci & Engn, Changsha 410000, Peoples R China
[2] Changsha Univ Sci & Technol, Sch Comp & Commun Engn, Changsha 410114, Peoples R China
[3] Natl Univ Def Technol, Coll Comp, Sci & Technol Parallel & Distributed Lab, Changsha 410000, Peoples R China
[4] Zhejiang Univ, Coll Control Sci & Engn, Hangzhou 310058, Zhejiang, Peoples R China
[5] Zhengzhou Univ Sci & Technol, Sch Informat Engn, Zhengzhou 450000, Peoples R China
基金
芬兰科学院;
关键词
D O I
10.1155/2021/4609741
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
As an important part of the brain, the dentate gyrus has an irreplaceable effect in the process of memory generation. Therefore, the study of the dentate gyrus model has important significance in the study of brain function. This paper, combined with the real anatomical structure of the dentate gyms, is based on the existing calculation model for studying the pathological state of the dentate gyrus, a network model of dentate gyrus based on bionics. Then, a simulation experiment on the normal dentate gyrus model is performed on the NEURON platform, the output of each neuron in the model is observed, and a conclusion that the improved model can respond to stimuli, generate action potentials, and transmit them along with the neural network is made. At the same time, the output results are compared with the existing pathological models, and the characteristics of the stimulus response between neurons in the dentate gyrus under normal physiological conditions are obtained. Finally, according to the semiquantitative classification definition and quantitative classification definition of the small-world network, the model is analyzed, and it is concluded that the improved dentate gyrus network model has small-world characteristics. Therefore, the neurons in the improved dentate gyrus model are tightly connected and can simulate the real dentate gyrus to a certain extent.
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页数:12
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