Pharmacological management of sleep after traumatic brain injury

被引:13
|
作者
Driver, Sangeeta [1 ,2 ]
Stork, Ryan [3 ]
机构
[1] Shirley Ryan Abilitylab, Brain Injury Med & Rehabil Program, 355 E Erie St, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Dept Phys Med & Rehabil, Chicago, IL 60611 USA
[3] Univ Michigan, Dept Phys Med & Rehabil, Med Sch, Ann Arbor, MI 48109 USA
关键词
Brain injury; sleep; medications; pharmacology; therapy; PRIMARY INSOMNIA; CONTROLLED-TRIAL; DOUBLE-BLIND; HEAD-INJURY; MELATONIN; PLACEBO; DISORDERS; TRAZODONE; RECOVERY; DISTURBANCE;
D O I
10.3233/NRE-182536
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Sleep-wake disturbances (SWD) are prevalent in the traumatic brain injury (TBI) population and may exacerbate related neurobehavioral impairments. As such, it is important to recognize and treat SWD early to allow for optimal cognitive recovery following a TBI. A number of medications are currently available for treatment of SWD. However, most research in this area has historically focused on neurologically intact populations. This article reviews key pharmacologic treatment principles and agents to consider for use in the treatment of TBI-related SWD. In addition, it highlights available research literature that has examined the use of sleep medications in this unique population.
引用
收藏
页码:347 / 353
页数:7
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