MICROBUBBLE-ASSISTED ULTRASOUND FOR IMAGING AND THERAPY OF MELANOMA SKIN CANCER: A SYSTEMATIC REVIEW

被引:5
|
作者
Avry, Francois [1 ]
Mousset, Coralie [1 ,2 ]
Oujagir, Edward [1 ]
Bouakaz, Ayache [1 ]
Gouilleux-gruart, Valerie [2 ]
Thepault, Rose-anne [1 ]
Renault, Sylvaine [1 ]
Marouillat, Sylviane [1 ]
Machet, Laurent [1 ,3 ]
Escoffrea, Jean-michel [1 ,4 ]
机构
[1] Univ Tours, INSERM, UMR 1253, iBrain, Tours, France
[2] Univ Tours, GICC EA 7501, Tours, France
[3] Tours Univ Hosp, Dept Dermatol, Tours, France
[4] Univ Tours, INSERM, UMR 1253, 10 Bd Tonnelle, Tours 37044, France
来源
ULTRASOUND IN MEDICINE AND BIOLOGY | 2022年 / 48卷 / 11期
关键词
Melanoma; Ultrasound; Microbubble; Imaging; Drug delivery; Therapy; CONTRAST-ENHANCED ULTRASOUND; SENTINEL LYMPH-NODES; CUTANEOUS MELANOMA; METASTATIC MELANOMA; MALIGNANT-MELANOMA; DRUG-DELIVERY; QUANTITATIVE ASSESSMENT; PERFUSION PARAMETERS; LOADED MICROBUBBLES; XENOGRAFT MODEL;
D O I
10.1016/j.ultrasmedbio.2022.06.021
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
technological developments in ultrasound (US) imaging and ultrasound contrast agents (UCAs) have improved diagnostic confidence in echography. In the clinical management of melanoma, contrast -enhanced ultrasound (CEUS) imaging complements conventional US imaging (i.e., high-resolution US and Dopp-ler imaging) for clinical examination and therapeutic follow-up. These developments have set into motion the combined use of ultrasound and UCAs as a new modality for drug delivery. This modality, called sonoporation, has emerged as a non-invasive, targeted and safe method for the delivery of therapeutic drugs into melanoma. This review focuses on the results and prospects of using US and UCAs as dual modalities for CEUS imaging and melanoma treatment. (E-mail: jean-michel.escoffre@univ-tours.fr) (c) 2022 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
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页码:2174 / 2198
页数:25
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