Physicochemical properties approach to the identification of a histamine H3 receptor antagonist for the treatment of ADHD

被引:0
|
作者
Wager, Travis T. [1 ]
机构
[1] Pfizer Global Res & Dev, Discovery Neurosci Med Chem, Groton, CT 06340 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
31-MEDI
引用
收藏
页数:1
相关论文
共 50 条
  • [1] A scalable synthesis of a histamine H3 receptor antagonist
    Mani, NS
    Jablonowski, JA
    Jones, TK
    JOURNAL OF ORGANIC CHEMISTRY, 2004, 69 (23): : 8115 - 8117
  • [2] Influence of bulky substituents on histamine H3 receptor agonist/antagonist properties
    Sasse, A
    Ligneau, X
    Rouleau, A
    Elz, S
    Ganellin, CR
    Arrang, JM
    Schwartz, JC
    Schunack, W
    Stark, H
    JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (18) : 4000 - 4010
  • [3] Identification of histamine H3 receptor antagonists
    Del Tredici, Andria Lee
    Eskildsen, Jorgen
    Andersen, Carsten B.
    Ma, Jian-Nong
    Ohrmund, Steven
    Petersen, Lauren
    Littler, Pey-Lih
    Nugyen, Derek
    Fairbairn, Luke
    Lameh, Jelveh
    Currier, Erika A.
    Schiffer, Hans H.
    Burstein, Ethan
    Olsson, Roger
    Piu, Fabrice
    FASEB JOURNAL, 2007, 21 (06): : A790 - A790
  • [4] Discovery of a Potent Thiadiazole Class of Histamine H3 Receptor Antagonist for the Treatment of Diabetes
    Rao, Ashwin U.
    Shao, Ning
    Aslanian, Robert G.
    Chan, Tin-Yau
    Degrado, Sylvia J.
    Wang, Li
    McKittrick, Brian
    Senior, Mary
    West, Robert E., Jr.
    Williams, Shirley M.
    Wu, Ren-Long
    Hwa, Joyce
    Patel, Bhuneshwari
    Zheng, Shuqin
    Sondey, Christopher
    Palani, Anandan
    ACS MEDICINAL CHEMISTRY LETTERS, 2012, 3 (03): : 198 - 202
  • [5] Identification of histamine receptors, and role of the histamine H3 receptor in obesity
    Kotani, H
    Takahashi, K
    Tokita, S
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005, 97 : 49P - 49P
  • [6] HISTAMINE H3 ANTAGONIST PROPERTIES AND EFFICACY IN CNS MODELS
    Cowart, M.
    INFLAMMATION RESEARCH, 2010, 59 : S333 - S333
  • [7] Evaluations of wake promoting effects of histamine H3 antagonist in H3 receptor knockout mice
    Okuro, M.
    Matsumura, M.
    Fujiki, N.
    Nishino, S.
    SLEEP, 2008, 31 : A220 - A221
  • [8] The effects of histamine H3 antagonist in the animal model of ADHD with neonatal habenula lesion
    Goto, Yukiori
    Lee, Young-A.
    NEUROSCIENCE RESEARCH, 2011, 71 : E402 - E402
  • [9] The histamine H3 receptor: Clinical applications of antagonist/inverse agonists
    Arrang, J. M.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 : S11 - S11
  • [10] Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics
    von Coburg, Y.
    Kottke, T.
    Weizel, L.
    Ligneau, X.
    Stark, H.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (02) : 538 - 542