A new triterpenoid saponin with nine sugar units from Anemone amurensis (Korsh.) Kom

被引：0
|
作者：
Lv, Chong-Ning [1 ]
Zhao, Ying [1 ]
Lu, Jin-Cai [1 ]
机构：
[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2021年 / 35卷 / 23期
基金：
中国国家自然科学基金;
关键词：
Anemone amurensis (Korsh; ) Kom; triterpenoid saponin; cytotoxic activity; RHIZOME;
D O I：
10.1080/14786419.2020.1765344
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new triterpenoid saponin named Anemonside A (1) was isolated from the rhizome of Anemone amurensis (Korsh.) Kom. Its structure was determined by chemical and spectral analysis, including 1D, 2D NMR data, HRESIMS and hydrolysis reaction. The new saponin contains nine sugar units with two O-linked sugar chains, which is relatively rare in natural products. In addition, the cytotoxic activity of Anemonside A was evaluated by against A549 and HepG2 cell lines with the MTT method and showed no cytotoxic activity with IC50 over 100 mu M.
引用
收藏
页码：5030 / 5035
页数：6
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