Design of Three-cascade Combinatorial Molecular Logic Circuit Based on DNA Strand Displacement

The research content of DNA computing is various and complex. The construction of DNA complex logic circuit belongs to an important research branch of DNA computing, in which the construction of logic gate belongs to the basic research of DNA complex logic circuit construction. The design of a simpler logic gate is used to provide a reference for researchers to build complex circuits and save valuable time for basic research. In order to solve the above problems, the idea of enable control end and DNA strand displacement technique are used to design three kinds of DNA combinatorial logic gates: AND-OR gate, NAND-NOR gate and XOR-XNOR gate. The results show that the three kinds of combinatorial logic gates can realize six kinds of logic operation functions, and the multi-stage combinatorial molecular logic circuits are successfully constructed by using the combinatorial logic gates, which provides more solutions for DNA calculation. It promotes the development of DNA computer.