High-speed camera with real time processing for frequency domain imaging

被引：2
|
作者：
Shia, Victor [1 ]
Watt, David [2 ]
Faris, Gregory W. [1 ]
机构：
[1] SRI Int, Div Phys Sci, Menlo Pk, CA 94025 USA
[2] SRI Int, Engn & Syst Grp, Menlo Pk, CA 94025 USA
来源：
BIOMEDICAL OPTICS EXPRESS | 2011年 / 2卷 / 07期
基金：
美国国家科学基金会;
关键词：
TURBID MEDIA; TISSUE; OPTIMIZATION; ABSORPTION; PRECISION; LIGHT;
D O I：
10.1364/BOE.2.001931
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We describe a high-speed camera system for frequency domain imaging suitable for applications such as in vivo diffuse optical imaging and fluorescence lifetime imaging. 14-bit images are acquired at 2 gigapixels per second and analyzed with real-time pipeline processing using field programmable gate arrays (FPGAs). Performance of the camera system has been tested both for RF-modulated laser imaging in combination with a gain-modulated image intensifier and a simpler system based upon an LED light source. System amplitude and phase noise are measured and compared against theoretical expressions in the shot noise limit presented for different frequency domain configurations. We show the camera itself is capable of shot noise limited performance for amplitude and phase in as little as 3 ms, and when used in combination with the intensifier the noise levels are nearly shot noise limited. The best phase noise in a single pixel is 0.04 degrees for a 1 s integration time. (C) 2011 Optical Society of America
引用
收藏
页码：1931 / 1945
页数：15
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