Rapid inversion of the prevalences of macrolide resistance phenotypes paralleled by a diversification of T and emm types among Streptococcus pyogenes in Portugal
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Silva-Costa, C
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Inst Mol Med, Microbiol Lab, Mol Microbiol & Infect Unit, Lisbon Fac Med, P-1649028 Lisbon, PortugalInst Mol Med, Microbiol Lab, Mol Microbiol & Infect Unit, Lisbon Fac Med, P-1649028 Lisbon, Portugal
Silva-Costa, C
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Ramirez, A
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Inst Mol Med, Microbiol Lab, Mol Microbiol & Infect Unit, Lisbon Fac Med, P-1649028 Lisbon, PortugalInst Mol Med, Microbiol Lab, Mol Microbiol & Infect Unit, Lisbon Fac Med, P-1649028 Lisbon, Portugal
Ramirez, A
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Meto-Cristino, J
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Inst Mol Med, Microbiol Lab, Mol Microbiol & Infect Unit, Lisbon Fac Med, P-1649028 Lisbon, PortugalInst Mol Med, Microbiol Lab, Mol Microbiol & Infect Unit, Lisbon Fac Med, P-1649028 Lisbon, Portugal
Meto-Cristino, J
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[1] Inst Mol Med, Microbiol Lab, Mol Microbiol & Infect Unit, Lisbon Fac Med, P-1649028 Lisbon, Portugal
In Portugal erythromycin resistance of 26.6% (n = 352) remained constant during 1998 to 2003, however in 1998 the MLSB phenotype dominated (85%), whereas in 2003 the M phenotype prevailed (77%). A decline in T12/emm22 MLSB isolates could partially explain the drop in this phenotype, but the rise of the M phenotype was not due to clonal expansion.