Sex hormones, obesity and type 2 diabetes: is there a link?

被引：55
|
作者：
Gambineri, Alessandra [1 ]
Pelusi, Carla [1 ]
机构：
[1] Alma Mater Univ Bologna, Endocrinol Unit, Dept Med & Surg Sci, St Orsola Malpighi Hosp, Bologna, Italy
来源：
ENDOCRINE CONNECTIONS | 2019年 / 8卷 / 01期
关键词：
androgens; estrogens; sex; obesity; diabetes; POLYCYSTIC-OVARY-SYNDROME; LOW TESTOSTERONE LEVELS; METABOLIC SYNDROME; INSULIN-RESISTANCE; HYPOGONADOTROPIC HYPOGONADISM; BINDING GLOBULIN; YOUNG-WOMEN; OLDER MEN; RISK; ANDROGENS;
D O I：
10.1530/EC-18-0450
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
An imbalance in sex hormones has an important impact on type 2 diabetes (T2DM) mainly through the involvement of visceral adipose tissue. Androgens have an interesting sex-dimorphic association with T2DM, since hyperandrogenism in females and hypogonadism in males are risk factors for T2DM. Thus, treatments aimed at correcting hyperandrogenism in females and hypogonadism in males may prevent the development of T2DM or help in its treatment.
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收藏
页码：R1 / R9
页数：9
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