Technological Improvement of Synthesis for Nabumetone

被引：0

作者：

Chen, Xiaoquan ^{[1
]}

Zuo, Zhili ^{[2
]}

Qiu, Yuqin ^{[3
]}

Zhou, Xiuyan ^{[4
]}

Zhang, Changjun ^{[1
]}

Zhai, Hu ^{[1
]}

Shao, Huiying ^{[1
]}

Li, Baoqing ^{[1
]}

机构：

[1] Taishan Med Univ, Chem & Chem Engn Sch, Tai An 271000, Shandong, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China

[3] E China Normal Univ, Shanghai 200062, Peoples R China

[4] Sichuan Univ, Sch Chem Engn, Chengdu 610065, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 30卷 / 07期

关键词：

synthesis; nabumetone; ultrasound; improvement;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In order to explore new method for synthesis of nabumetone, a synthetic method was investigated by the treatment of 2-methoxy naphthalene under ultrasonic irradiation. The time of the new synthesis method would be shortened from 13.5 h to 7.5 h and yield would be increased from 23.9% to 39.4%. The structure of the synthetic compound was identified by IR, MS and H-1 NMR techniques.

引用

页码：1069 / 1071

页数：3

共 10 条

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