Association between Exposure to Particulate Matter Air Pollution during Early Childhood and Risk of Attention-Deficit/Hyperactivity Disorder in Taiwan

被引:10
|
作者
Fan, Hueng-Chuen [1 ,2 ,3 ]
Chen, Chuan-Mu [4 ,5 ,6 ]
Tsai, Jeng-Dau [7 ,8 ]
Chiang, Kuo-Liang [9 ,10 ]
Tsai, Stella Chin-Shaw [5 ,6 ,11 ]
Huang, Ching-Ying [12 ]
Lin, Cheng-Li [13 ]
Hsu, Chung Y. [14 ]
Chang, Kuang-Hsi [5 ,15 ,16 ,17 ]
机构
[1] Tungs Taichung Metroharbor Hosp, Dept Pediat, Taichung 435, Taiwan
[2] Jen Teh Jr Coll Med, Dept Rehabil Nursing & Management, Miaoli 356, Taiwan
[3] Natl Chung Hsing Univ, Agr Biotechnol Ctr, Dept Life Sci, Taichung 402, Taiwan
[4] Natl Chung Hsing Univ, iEGG & Anim Biotechnol Ctr, Rong Hsing Res Ctr Translat Med, Taichung 402, Taiwan
[5] Natl Chung Hsing Univ, Dept Life Sci, PhD Program Translat Med, Taichung 402, Taiwan
[6] Natl Chung Hsing Univ, Coll Life Sci, Rong Hsing Res Ctr Translat Med, Taichung 402, Taiwan
[7] Chung Shan Med Univ, Sch Med, Taichung 402, Taiwan
[8] Chung Shan Med Univ Hosp, Dept Pediat, Taichung 402, Taiwan
[9] Kuang Tien Gen Hosp, Dept Pediat Neurol, Taichung 433, Taiwan
[10] Hungkuang Univ, Dept Nutr, Taichung 433, Taiwan
[11] Tungs Taichung MetroHarbor Hosp, Dept Otolaryngol, Taichung 435, Taiwan
[12] Natl Chung Hsing Univ, Dept Food Sci & Biotechnol, Taichung 402, Taiwan
[13] China Med Univ Hosp, Management Off Hlth Data, Taichung 404, Taiwan
[14] China Med Univ, Grad Inst Clin Med Sci, Taichung 404, Taiwan
[15] TungsTaichung MetroHarbor Hosp, Dept Med Res, Taichung 435, Taiwan
[16] China Med Univ, Ctr Gen Educ, Taichung 404, Taiwan
[17] Jen Teh Jr Coll Med Nursing & Management, Gen Educ Ctr, Miaoli 356, Taiwan
关键词
attention-deficit; hyperactivity disorder (ADHD); particulate matter (PM); National Health Insurance Research Database (NHIRD); DEFICIT HYPERACTIVITY DISORDER; ADHD; CHILDREN; IMPACT;
D O I
10.3390/ijerph192316138
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
(1) Background: Recently, a growing number of studies have provided evidence to suggest a strong correlation between air pollution exposure and attention-deficit/hyperactivity disorder (ADHD). In this study, we assessed the relationship between early-life exposure to particulate matter (PM)(10), PM2.(5), and ADHD; (2) Methods: The National Health Insurance Research Database (NHIRD) contains the medical records, drug information, inspection data, etc., of the people of Taiwan, and, thus, could serve as an important research resource. Air pollution data were based on daily data from the Environmental Protection Administration Executive Yuan, R.O.C. (Taiwan). These included particulate matter (PM2.5 and PM10). The two databases were merged according to the living area of the insured and the location of the air quality monitoring station; (3) Results: The highest levels of air pollutants, including PM2.5 (adjusted hazard ratio (aHR) = 1.79; 95% confidence interval (CI) = 1.58-2.02) and PM10 (aHR = 1.53; 95% CI = 1.37-1.70), had a significantly higher risk of ADHD; (4) Conclusions: As such, measures for air quality control that meet the WHO air quality guidelines should be strictly and uniformly implemented by Taiwanese government authorities.
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页数:10
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