Multispectral optoacoustic tomography by means of normalized spectral ratio

被引：11
|
作者：
Jetzfellner, Thomas
Rosenthal, Amir
Buehler, Andreas
Englmeier, Karl-Hans
Razansky, Daniel
Ntziachristos, Vasilis [1 ]
机构：
[1] Tech Univ Munich, Inst Biol & Med Imaging, D-85764 Neuherberg, Germany
来源：
OPTICS LETTERS | 2011年 / 36卷 / 21期
基金：
欧洲研究理事会;
关键词：
IN-VIVO;
D O I：
10.1364/OL.36.004176
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Quantification of biomarkers using multispectral optoacoustic tomography can be challenging due to photon fluence variations with depth and spatially heterogeneous tissue optical properties. Herein we introduce a spectral ratio approach that accounts for photon fluence variations. The performance and imaging improvement achieved with the proposed method is showcased both numerically and experimentally in phantoms and mice. (C) 2011 Optical Society of America
引用
收藏
页码：4176 / 4178
页数：3
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