Dominant-negative STAT5A inhibits the constitutive activation of STAT5 and the factor-independent-growth of the HEL/Dami leukemic cell line.

被引：0
|
作者：
Liu, RY
Fan, C
Wang, X
Zuckerman, KS
机构：
[1] Univ S Florida, Div Med Oncol & Hematol, Tampa, FL USA
[2] Univ S Florida, Dept Biochem & Mol Biol, Tampa, FL USA
[3] H Lee Moffit Canc Ctr & Res Inst, Tampa, FL USA
来源：
EXPERIMENTAL HEMATOLOGY | 1998年 / 26卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
249
引用
收藏
页码：751 / 751
页数：1
相关论文
共 50 条
  • [1] Constitutive activation of STAT5 in growth factor-independent megakaryocytic cell lines.
    Liu, RY
    Fan, C
    Garcia, R
    Jove, R
    Zuckerman, KS
    EXPERIMENTAL HEMATOLOGY, 1996, 24 (09) : 463 - 463
  • [2] Positive selection of apoptosis-resistant cells correlates with activation of dominant-negative STAT5
    Bovolenta, C
    Testolin, L
    Benussi, L
    Lievens, PMJ
    Liboi, E
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (33) : 20779 - 20784
  • [3] Dominant-negative Stat5 inhibits growth and induces apoptosis in T47D-derived tumors in nude mice
    Yamashita, H
    Nishio, M
    Fujii, Y
    Iwase, H
    CANCER SCIENCE, 2004, 95 (08): : 662 - 665
  • [4] Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines
    Liu, RY
    Fan, C
    Garcia, R
    Jove, R
    Zuckerman, KS
    BLOOD, 1999, 93 (07) : 2369 - 2379
  • [5] Factor-independent growth of human megakaryocytic cell lines, Dami and Meg-01, is dependent on constitutive activation of JAK2 and STAT5, but not on activation of the MAP kinase pathway.
    Liu, RY
    Fan, C
    Garcia, R
    Jove, R
    Zuckerman, KS
    BLOOD, 1996, 88 (10) : 220 - 220
  • [6] Expression of dominant-negative STAT5 inhibits growth hormone- and prolactin-induced proliferation of insulin-producing cells
    Galsgaard, ED
    Friedrichsen, BN
    Nielsen, JH
    Moldrup, A
    DIABETES, 2001, 50 : S40 - S41
  • [7] Constitutive activation of zebrafish Stat5 expands hematopoietic cell populations in vivo
    Lewis, RS
    Stephenson, SEM
    Ward, AC
    EXPERIMENTAL HEMATOLOGY, 2006, 34 (02) : 179 - 187
  • [8] Dominant negative mutants implicate STAT5 in myeloid cell proliferation and neutrophil differentiation
    Ilaria, RL
    Hawley, RG
    Van Etten, RA
    BLOOD, 1999, 93 (12) : 4154 - 4166
  • [9] Degradation of STAT5 proteins in 3T3-L1 adipocytes is induced by TNF-α and cycloheximide in a manner independent of STAT5A activation
    Floyd, Z. Elizabeth
    Segura, Brant M.
    He, Fang
    Stephens, Jacqueline M.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2007, 292 (02): : E461 - E468
  • [10] Activated STAT5a and STAT5b homodimers exist constitutively in factor-independent Dami/HEL and Meg-01 cells and are cytokine-inducible in factor-dependent M07E cells.
    Liu, RY
    Fan, C
    EpplingBurnette, PK
    Djeu, JY
    Jove, R
    Zuckerman, KS
    EXPERIMENTAL HEMATOLOGY, 1997, 25 (08) : 588 - 588
12345