A Facile Synthesis of Bridged Polycyclic Naphthooxazocine Skeletons: Eight-Membered-Ring Constructions via Tandem Dinucleophilic Addition of Naphthalenols to Quinolinium Salts

被引：0

作者：

Moghaddam, Firouz Matloubi ^{[1
]}

Taheri, Salman ^{[1
]}

Mirjafary, Zohreh ^{[1
]}

Saeidian, Hamdollah ^{[2
]}

Kiamehr, Mostafa ^{[1
]}

Tafazzoli, Mohsen ^{[1
]}

机构：

[1] Sharif Univ Technol, Dept Chem, Lab Organ Synth & Nat Prod, Tehran, Iran

[2] Payame Noor Univ, Dept Sci, Zanjan, Iran

来源：

HELVETICA CHIMICA ACTA | 2011年 / 94卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The efficient synthesis of bridged polycyclic naphthooxazocines 3 via addition of naphthalenols 1 as a bis-nucleophile to N-alkylquinolinium salts 2 is described (Scheme 1 and Table 2). This new approach provides a powerful entry into polycyclic structures containing bicyclic N,O-acetals related to bioactive compounds.

引用

页码：142 / 147

页数：6

共 4 条

[1] The synthesis of dibenzazocines via tandem dinucleophilic addition of phenols to quinolinium salts
Moghaddam, Firouz Matloubi
Saeidian, Hamdollah
Kiamehr, Mostafa
Mirjafary, Zohreh
Taheri, Salman
ARKIVOC, 2010, : 91 - 100
[2] Synthesis of eight-membered hydroquinolines related to alkaloid skeletons via addition of 4-hydroxycoumarin or 4-hydroxypyran-2-one to quinolinium salts
Moghaddam, Firouz Matloubi
Mirjafary, Zohreh
Saeidian, Hamdollah
Taheri, Salman
Soltanzadeh, Bardia
TETRAHEDRON, 2010, 66 (21) : 3678 - 3681
[3] Efficient and green synthesis of new polycyclic procyanidin derivatives via tandem dinucleophilic addition of indolin-2-thiones to flavylium salts
Moghaddam, Firouz Matloubi
Foroushani, Behzad Koushki
Saeidian, Hamdollah
Nourian, Saghar
Mirjafary, Zohreh
Kiamehr, Mostafa
PURE AND APPLIED CHEMISTRY, 2011, 83 (03) : 709 - 713
[4] EFFICIENT SYNTHESIS OF BICYCLO[3.3.1]NONANE SYSTEMS VIA TANDEM 1,3-DINUCLEOPHILIC ADDITION OF 4-HYDROXY-2-QUINOLINONES TO QUINOLINIUM SALTS
Moghaddam, Firouz Matloubi
Mirjafary, Zohreh
Saeidian, Hamdollah
Foroushani, Behzad Koushki
Nourian, Saghar
SYNTHETIC COMMUNICATIONS, 2012, 42 (13) : 1941 - 1949

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