Clinical results of a concomitant boost radiotherapy technique for muscle-invasive bladder cancer

被引:2
|
作者
Piet, Anna H. M. [1 ]
Hulshof, Maarten C. C. M. [1 ]
Pieters, Bradley R. [1 ]
Pos, Floris J. [2 ]
de Reijke, Theo M. [3 ]
Koning, Caro C. E. [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Radiat Oncol, NL-1105 AZ Amsterdam, Netherlands
[2] Antoni Van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Radiat Oncol, Amsterdam, Netherlands
[3] Univ Amsterdam, Acad Med Ctr, Dept Urol, NL-1012 WX Amsterdam, Netherlands
关键词
concomitant boost; functional outcome; invasive bladder cancer; radiotherapy;
D O I
10.1007/s00066-008-1797-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To update the results of external radiotherapy with a focal concomitant boost technique on local control and bladder function in patients with muscle-invasive bladder cancer. Patients and Methods: The authors retrospectively evaluated 92 elderly or disabled patients with localized T2-4 N0-1 M0 transitional cell carcinoma of the bladder and a median age of 79 years, not suitable for radical surgery and treated between 1994 and 2005. Treatment consisted of a dose of 40 Gy/2 Gy to the small pelvis with a daily concomitant boost of 0.75 Gy to the tumor. Total dose was 55 Gy in 4 weeks. Results: Complete remission rate after evaluation by means of cystoscopy at 3 months was 78%. 3-year local control rate amounted to 56%, and 3-year overall survival to 36%. The posttreatment bladder capacity was comparable with the pretreatment capacity and was >= 200 ml in 81% of the cases. Mean bladder capacity did not deteriorate at longer follow-up. Conclusion: The local control rate after external beam radiotherapy in elderly patients with a focal concomitant boost for localized muscle-invasive bladder cancer was 56% at 3 years. Functional bladder outcome was good.
引用
收藏
页码:313 / 318
页数:6
相关论文
共 50 条
  • [1] Clinical results of a concomitant boost radiotherapy technique for muscle invasive bladder cancer
    Piet, A.
    Hulshof, M.
    Nabavi, S. Seyed
    de Reyke, T.
    Pos, F.
    RADIOTHERAPY AND ONCOLOGY, 2006, 81 : S531 - S531
  • [2] Long-term results of a concomitant boost radiotherapy technique for elderly patients with muscle-invasive bladder cancer
    Canyilmaz, Emine
    Yoney, Adnan
    Serdar, Lasif
    Uslu, Gonca Hanedan
    Aynaci, Ozlem
    Haciislamoglu, Emel
    Bahat, Zumrut
    Yavuz, Melek Nur
    JOURNAL OF GERIATRIC ONCOLOGY, 2015, 6 (04) : 316 - 323
  • [3] Concomitant boost radiotherapy for muscle invasive bladder cancer
    Pos, FJ
    van Tienhoven, G
    Hulshof, MCCM
    Koedooder, K
    González, DG
    RADIOTHERAPY AND ONCOLOGY, 2003, 68 (01) : 75 - 80
  • [4] Long-term results of a concomitant boost radiotherapy technique for elderly patients with muscle-invasive bladder cancer (vol 6, pg 316, 2015)
    Canyilmaz, Emine
    Yoney, Adnan
    Serdar, Lasif
    Uslu, Gonca Hanedan
    Aynaci, Ozlem
    Haciislamoglu, Emel
    Yavuz, Melek Nur
    JOURNAL OF GERIATRIC ONCOLOGY, 2017, 8 (02) : 148 - 148
  • [5] Muscle-invasive bladder cancer treated with TURB followed by concomitant boost with small reduction of radiotherapy field with or without of chemotherapy
    Nowak-Sadzikowska, Jadwiga
    Skora, Tomasz
    Szyszka-Charewicz, Bogumila
    Jakubowicz, Jerzy
    REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, 2016, 21 (01) : 31 - 36
  • [6] RESULTS OF RADIOTHERAPY ON URETERAL OBSTRUCTION IN MUSCLE-INVASIVE BLADDER-CANCER
    DELICHTENBERG, MH
    MISKOWIAK, J
    ROLFF, H
    BRITISH JOURNAL OF UROLOGY, 1995, 75 (02): : 197 - 199
  • [7] Stereotactic Ablative Radiotherapy Boost to Bladder Tumor for Bladder Preservation in Patients with Muscle-Invasive Bladder Cancer
    Qin, S. B.
    Gao, X. S.
    Yu, W.
    Zhang, C. J.
    Hao, H.
    Yao, L.
    Bai, Y.
    Li, H. Z.
    He, Z. S.
    Wang, D.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : S111 - S111
  • [9] Clinical Results of a Concomitant Boost Radiotherapy Technique for Muscle-Invasive Bladder CancerErgebnisse nach primärer perkutaner Radiotherapie mittels konkomitanter Boost-Technik nach transurethraler Resektion muskelinvasiver Harnblasenkarzinome
    Anna H. M. Piet
    Maarten C. C. M. Hulshof
    Bradley R. Pieters
    Floris J. Pos
    Theo M. de Reijke
    Caro C. E. Koning
    Strahlentherapie und Onkologie, 2008, 184 (6) : 313 - 318
  • [10] ONLINE ADAPTIVE RADIOTHERAPY FOR MUSCLE-INVASIVE BLADDER CANCER: RESULTS OF A PILOT STUDY
    Foroudi, Farshad
    Wong, Jacky
    Kron, Tomas
    Rolfo, Aldo
    Haworth, Annetre
    Roxby, Paul
    Thomas, Jessica
    Herschtal, A.
    Pham, Daniel
    Williams, Scott
    Tai, Keen Hun
    Duchesne, Gillian
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2011, 81 (03): : 765 - 771