Leptin receptor expression in human umbilical cord leucocytes

被引：0
|
作者：
García, AH
Rivera, H
Radzioch, D
Blanca, I
Bianco, NE
De Sanctis, JB
机构：
[1] Cent Univ Venezuela, Fac Med, Inst Immunol, Caracas, Venezuela
[2] Montreal Gen Hosp, Montreal, PQ H3G 1A4, Canada
来源：
MEDICAL SCIENCE RESEARCH | 1999年 / 27卷 / 04期
关键词：
leptin; leptin receptor; umbilical cord leucocytes;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We have assessed the expression of leptin receptor on human umbilical cord blood leucocytes using flow cytometry, by a specific antibody, in 12 normal newborns (seven females and five males). The expression was significantly (P<0.0001) higher in polymorphonuclear cells (70 +/- 6%) as compared to monocytes (23 +/- 4%) and lymphocytes (16 +/- 4%). There was no correlation between the weight or the sex of the newborn and the effect of leptin or the expression of its receptor. Future studies should ascertain the type of leptin receptor, its function and the role of this cytokine in cord blood cells. Med Sci Res 27:231-232 (C) 1999 Lippincott Williams & Wilkins.
引用
收藏
页码：231 / 232
页数：2
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