The humoral response to the tumor-suppressor gene-product p53 in human cancer: Implications for diagnosis and therapy

被引：83
|
作者：
Soussi, T
机构：
[1] Institut de Genetique Moleculaire, University P. et M. Curie, INSERM
来源：
IMMUNOLOGY TODAY | 1996年 / 17卷 / 08期
关键词：
D O I：
10.1016/0167-5699(96)30019-4
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Mutation of the tumor-suppressor gene y53 appears to be an important trigger for the development of a humoral response in cancer patients. As discussed here, diagnosis of an alteration in p53 can be used as a marker of unfavorable prognosis and indicate a potential target for immunotherapy.
引用
收藏
页码：354 / 356
页数：3
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